Gastrointestinal side effects of iron supplements: potential effects on gut microbiota
Iron deficiency anemia remains a significant problem in pediatric practice with its prevalence of 6–40% in the Russian Federation. Oral iron supplementation is the most common first-line treatment especially in outpatient setting. Despite adequate efficacy of oral supplementation, the problem of its...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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Ltd. “The National Academy of Pediatric Science and Innovation”
2022-11-01
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| Series: | Rossijskij Vestnik Perinatologii i Pediatrii |
| Subjects: | |
| Online Access: | https://www.ped-perinatology.ru/jour/article/view/1696 |
| _version_ | 1797875109293195264 |
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| author | E. A. Balashova I. L. Shadrina A. A. Pogodina |
| author_facet | E. A. Balashova I. L. Shadrina A. A. Pogodina |
| author_sort | E. A. Balashova |
| collection | DOAJ |
| description | Iron deficiency anemia remains a significant problem in pediatric practice with its prevalence of 6–40% in the Russian Federation. Oral iron supplementation is the most common first-line treatment especially in outpatient setting. Despite adequate efficacy of oral supplementation, the problem of its side effects and, primarily, gastrointestinal toxicity remains. This review examines the issue of the potential effect of iron supplementation on gut microbiota composition, presents data from studies in animal models and in clinical studies. |
| first_indexed | 2024-04-10T01:41:25Z |
| format | Article |
| id | doaj.art-77923912a49943d685ef3ed9a36b2b5a |
| institution | Directory Open Access Journal |
| issn | 1027-4065 2500-2228 |
| language | Russian |
| last_indexed | 2024-04-10T01:41:25Z |
| publishDate | 2022-11-01 |
| publisher | Ltd. “The National Academy of Pediatric Science and Innovation” |
| record_format | Article |
| series | Rossijskij Vestnik Perinatologii i Pediatrii |
| spelling | doaj.art-77923912a49943d685ef3ed9a36b2b5a2023-03-13T09:12:53ZrusLtd. “The National Academy of Pediatric Science and Innovation”Rossijskij Vestnik Perinatologii i Pediatrii1027-40652500-22282022-11-01675182610.21508/1027-4065-2022-67-5-18-261235Gastrointestinal side effects of iron supplements: potential effects on gut microbiotaE. A. Balashova0I. L. Shadrina1A. A. Pogodina2ФГБОУ ВО «Самарский государственный медицинский университет» Минздрава РоссииФГБОУ ВО «Самарский государственный медицинский университет» Минздрава России; ГБУЗ Самарской области «Самарская городская больница №7»ГБУЗ Самарской области «Самарская городская клинико-диагностическая поликлиника №14»Iron deficiency anemia remains a significant problem in pediatric practice with its prevalence of 6–40% in the Russian Federation. Oral iron supplementation is the most common first-line treatment especially in outpatient setting. Despite adequate efficacy of oral supplementation, the problem of its side effects and, primarily, gastrointestinal toxicity remains. This review examines the issue of the potential effect of iron supplementation on gut microbiota composition, presents data from studies in animal models and in clinical studies.https://www.ped-perinatology.ru/jour/article/view/1696детидефицит железасаплементация железамикробиота |
| spellingShingle | E. A. Balashova I. L. Shadrina A. A. Pogodina Gastrointestinal side effects of iron supplements: potential effects on gut microbiota Rossijskij Vestnik Perinatologii i Pediatrii дети дефицит железа саплементация железа микробиота |
| title | Gastrointestinal side effects of iron supplements: potential effects on gut microbiota |
| title_full | Gastrointestinal side effects of iron supplements: potential effects on gut microbiota |
| title_fullStr | Gastrointestinal side effects of iron supplements: potential effects on gut microbiota |
| title_full_unstemmed | Gastrointestinal side effects of iron supplements: potential effects on gut microbiota |
| title_short | Gastrointestinal side effects of iron supplements: potential effects on gut microbiota |
| title_sort | gastrointestinal side effects of iron supplements potential effects on gut microbiota |
| topic | дети дефицит железа саплементация железа микробиота |
| url | https://www.ped-perinatology.ru/jour/article/view/1696 |
| work_keys_str_mv | AT eabalashova gastrointestinalsideeffectsofironsupplementspotentialeffectsongutmicrobiota AT ilshadrina gastrointestinalsideeffectsofironsupplementspotentialeffectsongutmicrobiota AT aapogodina gastrointestinalsideeffectsofironsupplementspotentialeffectsongutmicrobiota |