MMP-7 Serum and Tissue Levels Are Associated with Poor Survival in Platinum-Treated Bladder Cancer Patients

MMP-7 Serum and Tissue Levels Are Associated with Poor Survival in Platinum-Treated Bladder Cancer Patients

Chemotherapy resistance is a main cause of therapeutic failure and death in bladder cancer. With the approval of immune checkpoint inhibitors, prediction of platinum treatment became of great clinical importance. Matrix metalloproteinase-7 (MMP-7) was shown to be involved in cisplatin resistance. Th...

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Bibliographic Details
Main Authors: Tibor Szarvas, Michèle J. Hoffmann, Csilla Olah, Eszter Szekely, Andras Kiss, Jochen Hess, Stephan Tschirdewahn, Boris Hadaschik, Vera Grotheer, Peter Nyirady, Anita Csizmarik, Melinda Varadi, Henning Reis
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Diagnostics
Subjects:
bladder cancer
MMP-7
cisplatin
chemotherapy
metastasis
prognosis
Online Access:https://www.mdpi.com/2075-4418/11/1/48

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