Pediatric Emergency Medicine Didactics and Simulation (PEMDAS): Serotonin Syndrome

Introduction Serotonin syndrome is caused by an accumulation of serotonin in the body from drug interactions or overdose of serotonergic medications, including commonly used antidepressants. Symptoms can be life-threatening and encompass both neurologic and cardiovascular toxicity, including agitati...

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Main Authors: Corinne Shubin, Shweta Iyer, Jean Pearce, Benjamin Lang, Isabel Gross, Daisy Ciener, Suzan Mazor, Ashley Keilman, Anita Thomas
Format: Article
Language:English
Published: Association of American Medical Colleges 2020-07-01
Series:MedEdPORTAL
Subjects:
Online Access:http://www.mededportal.org/doi/10.15766/mep_2374-8265.10928
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author Corinne Shubin
Shweta Iyer
Jean Pearce
Benjamin Lang
Isabel Gross
Daisy Ciener
Suzan Mazor
Ashley Keilman
Anita Thomas
author_facet Corinne Shubin
Shweta Iyer
Jean Pearce
Benjamin Lang
Isabel Gross
Daisy Ciener
Suzan Mazor
Ashley Keilman
Anita Thomas
author_sort Corinne Shubin
collection DOAJ
description Introduction Serotonin syndrome is caused by an accumulation of serotonin in the body from drug interactions or overdose of serotonergic medications, including commonly used antidepressants. Symptoms can be life-threatening and encompass both neurologic and cardiovascular toxicity, including agitation, seizure, tachycardia, rhabdomyolysis, and hyperthermia. Methods This simulation case was developed for pediatric emergency medicine fellows and emergency medicine residents in the pediatric emergency department and can be altered to accommodate other learners. The case involved a 16-year-old male, represented by a low- or high-fidelity manikin, who presented with altered mental status/agitation after an overdose of antidepressant medication. The team of learners was required to perform a primary and a secondary assessment; manage airway, breathing, and circulation; and recognize and initiate treatment for serotonin syndrome. The patient had a seizure resulting in airway compromise requiring advanced airway support, as well as developed rhabdomyolysis requiring aggressive fluid hydration. We created a debriefing guide and a participant evaluation form. Results Fifty-seven participants across five institutions completed this simulation, which included residents, fellows, faculty, and students. The scenario was rated by participants using a 5-point Likert scale and was generally well received. Participants rated the simulation case as effective in learning how to both recognize (M = 4.9) and manage (M = 4.8) serotonin syndrome. Discussion This pediatric emergency simulation scenario can be tailored for a range of learner backgrounds and simulation environments. We used the participant evaluation form to improve future iterations of the simulation.
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spelling doaj.art-7799ec8f245c44a9ab42b0451c1203e82022-12-21T18:02:23ZengAssociation of American Medical CollegesMedEdPORTAL2374-82652020-07-011610.15766/mep_2374-8265.10928Pediatric Emergency Medicine Didactics and Simulation (PEMDAS): Serotonin SyndromeCorinne Shubin0Shweta Iyer1Jean Pearce2Benjamin Lang3Isabel Gross4Daisy Ciener5Suzan Mazor6Ashley Keilman7Anita Thomas8Assistant Professor, Department of Pediatrics, Division of Emergency Medicine, University of Washington School of Medicine and Seattle Children's HospitalAssistant Professor, Pediatrics and Emergency Medicine, Weill Cornell Medical CollegeAssistant Professor, Department of Pediatrics, Division of Emergency Medicine, Medical College of WisconsinPediatrics Resident, Department of Pediatrics, University of Washington School of Medicine and Seattle Children's HospitalClinical Instructor, Department of Pediatrics, Division of Emergency Medicine, Yale University School of Medicine and Yale New Haven Children's HospitalAssistant Professor, Clinical Pediatrics, Division of Pediatric Emergency Medicine, Vanderbilt University Medical CenterDirector of Pediatric Toxicology, University of Washington School of Medicine and Seattle Children's Hospital; Associate Professor, Department of Pediatrics, Division of Emergency Medicine, University of Washington School of Medicine and Seattle Children's HospitalAssistant Professor, Department of Pediatrics, Division of Emergency Medicine, University of Washington School of Medicine and Seattle Children's HospitalAssistant Professor, Department of Pediatrics, Division of Emergency Medicine, University of Washington School of Medicine and Seattle Children's HospitalIntroduction Serotonin syndrome is caused by an accumulation of serotonin in the body from drug interactions or overdose of serotonergic medications, including commonly used antidepressants. Symptoms can be life-threatening and encompass both neurologic and cardiovascular toxicity, including agitation, seizure, tachycardia, rhabdomyolysis, and hyperthermia. Methods This simulation case was developed for pediatric emergency medicine fellows and emergency medicine residents in the pediatric emergency department and can be altered to accommodate other learners. The case involved a 16-year-old male, represented by a low- or high-fidelity manikin, who presented with altered mental status/agitation after an overdose of antidepressant medication. The team of learners was required to perform a primary and a secondary assessment; manage airway, breathing, and circulation; and recognize and initiate treatment for serotonin syndrome. The patient had a seizure resulting in airway compromise requiring advanced airway support, as well as developed rhabdomyolysis requiring aggressive fluid hydration. We created a debriefing guide and a participant evaluation form. Results Fifty-seven participants across five institutions completed this simulation, which included residents, fellows, faculty, and students. The scenario was rated by participants using a 5-point Likert scale and was generally well received. Participants rated the simulation case as effective in learning how to both recognize (M = 4.9) and manage (M = 4.8) serotonin syndrome. Discussion This pediatric emergency simulation scenario can be tailored for a range of learner backgrounds and simulation environments. We used the participant evaluation form to improve future iterations of the simulation.http://www.mededportal.org/doi/10.15766/mep_2374-8265.10928Serotonin SyndromeSimulationRhabdomyolysisSeizureAltered Mental StatusPediatric Emergency Medicine
spellingShingle Corinne Shubin
Shweta Iyer
Jean Pearce
Benjamin Lang
Isabel Gross
Daisy Ciener
Suzan Mazor
Ashley Keilman
Anita Thomas
Pediatric Emergency Medicine Didactics and Simulation (PEMDAS): Serotonin Syndrome
MedEdPORTAL
Serotonin Syndrome
Simulation
Rhabdomyolysis
Seizure
Altered Mental Status
Pediatric Emergency Medicine
title Pediatric Emergency Medicine Didactics and Simulation (PEMDAS): Serotonin Syndrome
title_full Pediatric Emergency Medicine Didactics and Simulation (PEMDAS): Serotonin Syndrome
title_fullStr Pediatric Emergency Medicine Didactics and Simulation (PEMDAS): Serotonin Syndrome
title_full_unstemmed Pediatric Emergency Medicine Didactics and Simulation (PEMDAS): Serotonin Syndrome
title_short Pediatric Emergency Medicine Didactics and Simulation (PEMDAS): Serotonin Syndrome
title_sort pediatric emergency medicine didactics and simulation pemdas serotonin syndrome
topic Serotonin Syndrome
Simulation
Rhabdomyolysis
Seizure
Altered Mental Status
Pediatric Emergency Medicine
url http://www.mededportal.org/doi/10.15766/mep_2374-8265.10928
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