EFFECT OF IMMUNOTHERAPY ACTIVATED T-LYMPHOCYTES ON CELLULAR IMMUNITY IN DIFFERENT FORMS OF ATOPIC DERMATITIS

The article describes the results of therapy with autologous activated. T-lymphocytes in patients with atopic dermatitis. Has been shown high clinical efficacy and safety of this therapy in the treatment of patients with both allergic and nonallergic form of the disease. In the allergic form observe...

Full description

Bibliographic Details
Main Authors: N. A. Shestakova, V. S. Kozhevnikov
Format: Article
Language:Russian
Published: Scientific Сentre for Family Health and Human Reproduction Problems 2012-05-01
Series:Acta Biomedica Scientifica
Subjects:
Online Access:https://www.actabiomedica.ru/jour/article/view/923
_version_ 1797237692536193024
author N. A. Shestakova
V. S. Kozhevnikov
author_facet N. A. Shestakova
V. S. Kozhevnikov
author_sort N. A. Shestakova
collection DOAJ
description The article describes the results of therapy with autologous activated. T-lymphocytes in patients with atopic dermatitis. Has been shown high clinical efficacy and safety of this therapy in the treatment of patients with both allergic and nonallergic form of the disease. In the allergic form observed more rapid positive changes, but in the opposite form of the efficiency was higher. Influence on cellular immunity in different forms differed. If the allergic form there was an increase of CD8+ T-cells in the nonallergic form — increased CD8+CD25+ T-cells and changes in delayed-type hypersensitivity.
first_indexed 2024-03-08T12:23:09Z
format Article
id doaj.art-7799fea7a2594070a0d0444592662e4a
institution Directory Open Access Journal
issn 2541-9420
2587-9596
language Russian
last_indexed 2024-04-24T17:23:47Z
publishDate 2012-05-01
publisher Scientific Сentre for Family Health and Human Reproduction Problems
record_format Article
series Acta Biomedica Scientifica
spelling doaj.art-7799fea7a2594070a0d0444592662e4a2024-03-28T07:49:04ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962012-05-0103(2)226230869EFFECT OF IMMUNOTHERAPY ACTIVATED T-LYMPHOCYTES ON CELLULAR IMMUNITY IN DIFFERENT FORMS OF ATOPIC DERMATITISN. A. Shestakova0V. S. Kozhevnikov1Research Institute of Medical Problems of the North SB RAMSResearch Institute of Clinical Immunology SB RAMSThe article describes the results of therapy with autologous activated. T-lymphocytes in patients with atopic dermatitis. Has been shown high clinical efficacy and safety of this therapy in the treatment of patients with both allergic and nonallergic form of the disease. In the allergic form observed more rapid positive changes, but in the opposite form of the efficiency was higher. Influence on cellular immunity in different forms differed. If the allergic form there was an increase of CD8+ T-cells in the nonallergic form — increased CD8+CD25+ T-cells and changes in delayed-type hypersensitivity.https://www.actabiomedica.ru/jour/article/view/923atopic dermatitist-cell vaccinationregulatory cellsantiergotypic response
spellingShingle N. A. Shestakova
V. S. Kozhevnikov
EFFECT OF IMMUNOTHERAPY ACTIVATED T-LYMPHOCYTES ON CELLULAR IMMUNITY IN DIFFERENT FORMS OF ATOPIC DERMATITIS
Acta Biomedica Scientifica
atopic dermatitis
t-cell vaccination
regulatory cells
antiergotypic response
title EFFECT OF IMMUNOTHERAPY ACTIVATED T-LYMPHOCYTES ON CELLULAR IMMUNITY IN DIFFERENT FORMS OF ATOPIC DERMATITIS
title_full EFFECT OF IMMUNOTHERAPY ACTIVATED T-LYMPHOCYTES ON CELLULAR IMMUNITY IN DIFFERENT FORMS OF ATOPIC DERMATITIS
title_fullStr EFFECT OF IMMUNOTHERAPY ACTIVATED T-LYMPHOCYTES ON CELLULAR IMMUNITY IN DIFFERENT FORMS OF ATOPIC DERMATITIS
title_full_unstemmed EFFECT OF IMMUNOTHERAPY ACTIVATED T-LYMPHOCYTES ON CELLULAR IMMUNITY IN DIFFERENT FORMS OF ATOPIC DERMATITIS
title_short EFFECT OF IMMUNOTHERAPY ACTIVATED T-LYMPHOCYTES ON CELLULAR IMMUNITY IN DIFFERENT FORMS OF ATOPIC DERMATITIS
title_sort effect of immunotherapy activated t lymphocytes on cellular immunity in different forms of atopic dermatitis
topic atopic dermatitis
t-cell vaccination
regulatory cells
antiergotypic response
url https://www.actabiomedica.ru/jour/article/view/923
work_keys_str_mv AT nashestakova effectofimmunotherapyactivatedtlymphocytesoncellularimmunityindifferentformsofatopicdermatitis
AT vskozhevnikov effectofimmunotherapyactivatedtlymphocytesoncellularimmunityindifferentformsofatopicdermatitis