EFFECT OF IMMUNOTHERAPY ACTIVATED T-LYMPHOCYTES ON CELLULAR IMMUNITY IN DIFFERENT FORMS OF ATOPIC DERMATITIS
The article describes the results of therapy with autologous activated. T-lymphocytes in patients with atopic dermatitis. Has been shown high clinical efficacy and safety of this therapy in the treatment of patients with both allergic and nonallergic form of the disease. In the allergic form observe...
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Format: | Article |
Language: | Russian |
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Scientific Сentre for Family Health and Human Reproduction Problems
2012-05-01
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Series: | Acta Biomedica Scientifica |
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Online Access: | https://www.actabiomedica.ru/jour/article/view/923 |
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author | N. A. Shestakova V. S. Kozhevnikov |
author_facet | N. A. Shestakova V. S. Kozhevnikov |
author_sort | N. A. Shestakova |
collection | DOAJ |
description | The article describes the results of therapy with autologous activated. T-lymphocytes in patients with atopic dermatitis. Has been shown high clinical efficacy and safety of this therapy in the treatment of patients with both allergic and nonallergic form of the disease. In the allergic form observed more rapid positive changes, but in the opposite form of the efficiency was higher. Influence on cellular immunity in different forms differed. If the allergic form there was an increase of CD8+ T-cells in the nonallergic form — increased CD8+CD25+ T-cells and changes in delayed-type hypersensitivity. |
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format | Article |
id | doaj.art-7799fea7a2594070a0d0444592662e4a |
institution | Directory Open Access Journal |
issn | 2541-9420 2587-9596 |
language | Russian |
last_indexed | 2024-04-24T17:23:47Z |
publishDate | 2012-05-01 |
publisher | Scientific Сentre for Family Health and Human Reproduction Problems |
record_format | Article |
series | Acta Biomedica Scientifica |
spelling | doaj.art-7799fea7a2594070a0d0444592662e4a2024-03-28T07:49:04ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962012-05-0103(2)226230869EFFECT OF IMMUNOTHERAPY ACTIVATED T-LYMPHOCYTES ON CELLULAR IMMUNITY IN DIFFERENT FORMS OF ATOPIC DERMATITISN. A. Shestakova0V. S. Kozhevnikov1Research Institute of Medical Problems of the North SB RAMSResearch Institute of Clinical Immunology SB RAMSThe article describes the results of therapy with autologous activated. T-lymphocytes in patients with atopic dermatitis. Has been shown high clinical efficacy and safety of this therapy in the treatment of patients with both allergic and nonallergic form of the disease. In the allergic form observed more rapid positive changes, but in the opposite form of the efficiency was higher. Influence on cellular immunity in different forms differed. If the allergic form there was an increase of CD8+ T-cells in the nonallergic form — increased CD8+CD25+ T-cells and changes in delayed-type hypersensitivity.https://www.actabiomedica.ru/jour/article/view/923atopic dermatitist-cell vaccinationregulatory cellsantiergotypic response |
spellingShingle | N. A. Shestakova V. S. Kozhevnikov EFFECT OF IMMUNOTHERAPY ACTIVATED T-LYMPHOCYTES ON CELLULAR IMMUNITY IN DIFFERENT FORMS OF ATOPIC DERMATITIS Acta Biomedica Scientifica atopic dermatitis t-cell vaccination regulatory cells antiergotypic response |
title | EFFECT OF IMMUNOTHERAPY ACTIVATED T-LYMPHOCYTES ON CELLULAR IMMUNITY IN DIFFERENT FORMS OF ATOPIC DERMATITIS |
title_full | EFFECT OF IMMUNOTHERAPY ACTIVATED T-LYMPHOCYTES ON CELLULAR IMMUNITY IN DIFFERENT FORMS OF ATOPIC DERMATITIS |
title_fullStr | EFFECT OF IMMUNOTHERAPY ACTIVATED T-LYMPHOCYTES ON CELLULAR IMMUNITY IN DIFFERENT FORMS OF ATOPIC DERMATITIS |
title_full_unstemmed | EFFECT OF IMMUNOTHERAPY ACTIVATED T-LYMPHOCYTES ON CELLULAR IMMUNITY IN DIFFERENT FORMS OF ATOPIC DERMATITIS |
title_short | EFFECT OF IMMUNOTHERAPY ACTIVATED T-LYMPHOCYTES ON CELLULAR IMMUNITY IN DIFFERENT FORMS OF ATOPIC DERMATITIS |
title_sort | effect of immunotherapy activated t lymphocytes on cellular immunity in different forms of atopic dermatitis |
topic | atopic dermatitis t-cell vaccination regulatory cells antiergotypic response |
url | https://www.actabiomedica.ru/jour/article/view/923 |
work_keys_str_mv | AT nashestakova effectofimmunotherapyactivatedtlymphocytesoncellularimmunityindifferentformsofatopicdermatitis AT vskozhevnikov effectofimmunotherapyactivatedtlymphocytesoncellularimmunityindifferentformsofatopicdermatitis |