Interaction Between BGLF2 and BBLF1 Is Required for the Efficient Production of Infectious Epstein–Barr Virus Particles

Interaction Between BGLF2 and BBLF1 Is Required for the Efficient Production of Infectious Epstein–Barr Virus Particles

BGLF2 is a tegument protein of the Epstein–Barr virus (EBV). This study finds that BGLF2 is expressed in the late stage of the EBV lytic cycle. Microscopic investigations reveal that BGLF2 is present in both the nucleus and the cytoplasm and colocalized with BBLF1 and gp350 at juxtanuclear regions i...

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Bibliographic Details
Main Authors: Chien-Hui Hung, Ya-Fang Chiu, Wen-Hung Wang, Lee-Wen Chen, Pey-Jium Chang, Tsung-Yu Huang, Ying-Ju Lin, Wan-Ju Tsai, Chia-Ching Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Microbiology
Subjects:
BGLF2
BBLF1
maturation
final envelopment
acidic cluster
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.03021/full

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