Virtual non-enhanced dual-energy computed tomography reconstruction: a candidate to replace true non-enhanced computed tomography scans in the setting of suspected liver alveolar echinococcosis
PURPOSEWhen a suspected hepatic alveolar echinococcosis (AE) lesion is detected on a contrast enhanced computed tomography (CT) scan, an additional triphasic or non-enhanced CT scan is required to determine the presence of calcification and enhancement. As a result, imaging costs and exposure to ion...
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2023-11-01
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| Series: | Diagnostic and Interventional Radiology |
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| Online Access: |
http://www.dirjournal.org/archives/archive-detail/article-preview/virtual-non-enhanced-dual-energy-computed-tomograp/59897
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| _version_ | 1827767304210874368 |
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| author | Mecit Kantarcı Sonay Aydın Ayşegül Kahraman Hayri Oğul Barış İrgül Akın Levent |
| author_facet | Mecit Kantarcı Sonay Aydın Ayşegül Kahraman Hayri Oğul Barış İrgül Akın Levent |
| author_sort | Mecit Kantarcı |
| collection | DOAJ |
| description | PURPOSEWhen a suspected hepatic alveolar echinococcosis (AE) lesion is detected on a contrast enhanced computed tomography (CT) scan, an additional triphasic or non-enhanced CT scan is required to determine the presence of calcification and enhancement. As a result, imaging costs and exposure to ionizing radiation will increase. We can create a non-enhanced series from routine contrast-enhanced images using dual-energy CT (DECT) and virtual non-enhanced (VNE) images. This study’s objective is to assess virtual non-enhanced DECT reconstruction as a potential diagnostic tool for hepatic AE.METHODSTriphasic CT scans and a routine dual energy venous phase were acquired using a third-generation DECT system. A commercially available software package was used to generate VNE images. Individual evaluations were conducted by two radiologists.RESULTSThe study population consisted of 100 patients (30 AE, 70 other solid liver masses). All AE cases were diagnosed [no false positives/negatives, 95% confidence interval (CI) sensitivity: 91.3%–100%; 95% CI specificity: 95.3%–100%]. Interrater agreement was k: 0.79. In total, 33 (33.00%) of the patients had AE, which was detected using both true non-enhanced (TNE) and VNE images. The mean dose-length product of a standard triphasic CT was significantly higher than biphasic dual-energy VNE images.CONCLUSIONIn terms of diagnostic confidence, VNE images are comparable with actual non-enhanced imaging when evaluating hepatic AE. Further, VNE images could replace TNE images with a substantial radiation dose reduction. Advances in knowledge: hepatic cystic echinococcosis and AE are serious and severe diseases with high fatality rates and a poor prognosis if managed incorrectly, especially AE. Moreover, VNE images produce equal diagnostic confidence to TNE images for assessing liver AE, with a significant reduction in radiation dose. |
| first_indexed | 2024-03-11T11:56:51Z |
| format | Article |
| id | doaj.art-779ec1f4a7f44912b86dd154e5ede90d |
| institution | Directory Open Access Journal |
| issn | 1305-3825 1305-3612 |
| language | English |
| last_indexed | 2024-03-11T11:56:51Z |
| publishDate | 2023-11-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Diagnostic and Interventional Radiology |
| spelling | doaj.art-779ec1f4a7f44912b86dd154e5ede90d2023-11-08T12:27:32ZengGalenos Publishing HouseDiagnostic and Interventional Radiology1305-38251305-36122023-11-0129673674010.4274/dir.2023.22180613049054Virtual non-enhanced dual-energy computed tomography reconstruction: a candidate to replace true non-enhanced computed tomography scans in the setting of suspected liver alveolar echinococcosisMecit Kantarcı0Sonay Aydın1Ayşegül Kahraman2Hayri Oğul3Barış İrgül4Akın Levent5 Department of Radiology, Atatürk University, Faculty of Medicine, Erzurum, Turkey Department of Radiology, Erzincan Binali Yıldırım University, Faculty of Medicine, Erzincan, Turkey Department of Radiology, İnönü University, Faculty of Medicine, Malatya, Turkey Department of Radiology, Atatürk University, Faculty of Medicine, Erzurum, Turkey Department of Radiology, Erzincan Binali Yıldırım University, Faculty of Medicine, Erzincan, Turkey Department of Radiology, Erzincan Binali Yıldırım University, Faculty of Medicine, Erzincan, Turkey PURPOSEWhen a suspected hepatic alveolar echinococcosis (AE) lesion is detected on a contrast enhanced computed tomography (CT) scan, an additional triphasic or non-enhanced CT scan is required to determine the presence of calcification and enhancement. As a result, imaging costs and exposure to ionizing radiation will increase. We can create a non-enhanced series from routine contrast-enhanced images using dual-energy CT (DECT) and virtual non-enhanced (VNE) images. This study’s objective is to assess virtual non-enhanced DECT reconstruction as a potential diagnostic tool for hepatic AE.METHODSTriphasic CT scans and a routine dual energy venous phase were acquired using a third-generation DECT system. A commercially available software package was used to generate VNE images. Individual evaluations were conducted by two radiologists.RESULTSThe study population consisted of 100 patients (30 AE, 70 other solid liver masses). All AE cases were diagnosed [no false positives/negatives, 95% confidence interval (CI) sensitivity: 91.3%–100%; 95% CI specificity: 95.3%–100%]. Interrater agreement was k: 0.79. In total, 33 (33.00%) of the patients had AE, which was detected using both true non-enhanced (TNE) and VNE images. The mean dose-length product of a standard triphasic CT was significantly higher than biphasic dual-energy VNE images.CONCLUSIONIn terms of diagnostic confidence, VNE images are comparable with actual non-enhanced imaging when evaluating hepatic AE. Further, VNE images could replace TNE images with a substantial radiation dose reduction. Advances in knowledge: hepatic cystic echinococcosis and AE are serious and severe diseases with high fatality rates and a poor prognosis if managed incorrectly, especially AE. Moreover, VNE images produce equal diagnostic confidence to TNE images for assessing liver AE, with a significant reduction in radiation dose. http://www.dirjournal.org/archives/archive-detail/article-preview/virtual-non-enhanced-dual-energy-computed-tomograp/59897 dectvirtual non-enhancedalveolar echinococcosisdlpradiation |
| spellingShingle | Mecit Kantarcı Sonay Aydın Ayşegül Kahraman Hayri Oğul Barış İrgül Akın Levent Virtual non-enhanced dual-energy computed tomography reconstruction: a candidate to replace true non-enhanced computed tomography scans in the setting of suspected liver alveolar echinococcosis Diagnostic and Interventional Radiology dect virtual non-enhanced alveolar echinococcosis dlp radiation |
| title | Virtual non-enhanced dual-energy computed tomography reconstruction: a candidate to replace true non-enhanced computed tomography scans in the setting of suspected liver alveolar echinococcosis |
| title_full | Virtual non-enhanced dual-energy computed tomography reconstruction: a candidate to replace true non-enhanced computed tomography scans in the setting of suspected liver alveolar echinococcosis |
| title_fullStr | Virtual non-enhanced dual-energy computed tomography reconstruction: a candidate to replace true non-enhanced computed tomography scans in the setting of suspected liver alveolar echinococcosis |
| title_full_unstemmed | Virtual non-enhanced dual-energy computed tomography reconstruction: a candidate to replace true non-enhanced computed tomography scans in the setting of suspected liver alveolar echinococcosis |
| title_short | Virtual non-enhanced dual-energy computed tomography reconstruction: a candidate to replace true non-enhanced computed tomography scans in the setting of suspected liver alveolar echinococcosis |
| title_sort | virtual non enhanced dual energy computed tomography reconstruction a candidate to replace true non enhanced computed tomography scans in the setting of suspected liver alveolar echinococcosis |
| topic | dect virtual non-enhanced alveolar echinococcosis dlp radiation |
| url |
http://www.dirjournal.org/archives/archive-detail/article-preview/virtual-non-enhanced-dual-energy-computed-tomograp/59897
|
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