Acute Genital Ulcers in a Woman Secondary to COVID-19 Infection: A Case Report

Jia Zhang,1,* Danni Wang,1,* Mingjing Chen,1 Jiajun Li,2 Wenxiang Huang1 1Department of Geriatrics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 2Department of Infectious Diseases, the First Affiliated Hospital of Chongqing Med...

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Main Authors: Zhang J, Wang D, Chen M, Li J, Huang W
Format: Article
Language:English
Published: Dove Medical Press 2024-01-01
Series:Clinical, Cosmetic and Investigational Dermatology
Subjects:
Online Access:https://www.dovepress.com/acute-genital-ulcers-in-a-woman-secondary-to-covid-19-infection-a-case-peer-reviewed-fulltext-article-CCID
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author Zhang J
Wang D
Chen M
Li J
Huang W
author_facet Zhang J
Wang D
Chen M
Li J
Huang W
author_sort Zhang J
collection DOAJ
description Jia Zhang,1,* Danni Wang,1,* Mingjing Chen,1 Jiajun Li,2 Wenxiang Huang1 1Department of Geriatrics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 2Department of Infectious Diseases, the First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wenxiang Huang, Department of Geriatrics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China, Tel +86 13883533808, Email wenxiang_huang@163.comAbstract: Acute genital ulcers (AGU) have been associated with various pathogens, such as Epstein–Barr virus (EBV) and cytomegalovirus (CMV). However, cases of AGU associated with coronavirus disease 2019 (COVID-19) are rare, and this disease significantly impairs human quality of life. In this case, we report a 37-year-old woman who presented with a five-day history of a painful genital ulcer and fever. A month earlier, she had experienced a COVID-19 infection that resolved without medical therapy. Physical examination revealed that multiple asymmetric ulcers presented on labia minora covered with whitish exudates. The patient, without any high-risk sexual behavior, or a personal or family history of autoimmune disorders or inflammatory bowel disease, was diagnosed with COVID-19-related AGU after ruling out other infectious and immune diseases. Following a two-week treatment of oral prednisone, her vulvar edema, ulcers, and fever improved significantly. This case suggests that AGU may be triggered by a COVID-19 infection.Keywords: COVID-19, SARS-CoV-2, acute genital ulcers, fever
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spelling doaj.art-779edb823a1245afadb90c9065cd8a6d2024-01-07T18:06:43ZengDove Medical PressClinical, Cosmetic and Investigational Dermatology1178-70152024-01-01Volume 17313489508Acute Genital Ulcers in a Woman Secondary to COVID-19 Infection: A Case ReportZhang JWang DChen MLi JHuang WJia Zhang,1,* Danni Wang,1,* Mingjing Chen,1 Jiajun Li,2 Wenxiang Huang1 1Department of Geriatrics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 2Department of Infectious Diseases, the First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wenxiang Huang, Department of Geriatrics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China, Tel +86 13883533808, Email wenxiang_huang@163.comAbstract: Acute genital ulcers (AGU) have been associated with various pathogens, such as Epstein–Barr virus (EBV) and cytomegalovirus (CMV). However, cases of AGU associated with coronavirus disease 2019 (COVID-19) are rare, and this disease significantly impairs human quality of life. In this case, we report a 37-year-old woman who presented with a five-day history of a painful genital ulcer and fever. A month earlier, she had experienced a COVID-19 infection that resolved without medical therapy. Physical examination revealed that multiple asymmetric ulcers presented on labia minora covered with whitish exudates. The patient, without any high-risk sexual behavior, or a personal or family history of autoimmune disorders or inflammatory bowel disease, was diagnosed with COVID-19-related AGU after ruling out other infectious and immune diseases. Following a two-week treatment of oral prednisone, her vulvar edema, ulcers, and fever improved significantly. This case suggests that AGU may be triggered by a COVID-19 infection.Keywords: COVID-19, SARS-CoV-2, acute genital ulcers, feverhttps://www.dovepress.com/acute-genital-ulcers-in-a-woman-secondary-to-covid-19-infection-a-case-peer-reviewed-fulltext-article-CCIDcovid-19sars-cov-2acute genital ulcersfever
spellingShingle Zhang J
Wang D
Chen M
Li J
Huang W
Acute Genital Ulcers in a Woman Secondary to COVID-19 Infection: A Case Report
Clinical, Cosmetic and Investigational Dermatology
covid-19
sars-cov-2
acute genital ulcers
fever
title Acute Genital Ulcers in a Woman Secondary to COVID-19 Infection: A Case Report
title_full Acute Genital Ulcers in a Woman Secondary to COVID-19 Infection: A Case Report
title_fullStr Acute Genital Ulcers in a Woman Secondary to COVID-19 Infection: A Case Report
title_full_unstemmed Acute Genital Ulcers in a Woman Secondary to COVID-19 Infection: A Case Report
title_short Acute Genital Ulcers in a Woman Secondary to COVID-19 Infection: A Case Report
title_sort acute genital ulcers in a woman secondary to covid 19 infection a case report
topic covid-19
sars-cov-2
acute genital ulcers
fever
url https://www.dovepress.com/acute-genital-ulcers-in-a-woman-secondary-to-covid-19-infection-a-case-peer-reviewed-fulltext-article-CCID
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AT chenm acutegenitalulcersinawomansecondarytocovid19infectionacasereport
AT lij acutegenitalulcersinawomansecondarytocovid19infectionacasereport
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