Aspergillus fumigatus secretes a protease(s) that displays in silico binding affinity towards the SARS-CoV-2 spike protein and mediates SARS-CoV-2 pseudovirion entry into HEK-293T cells

Aspergillus fumigatus secretes a protease(s) that displays in silico binding affinity towards the SARS-CoV-2 spike protein and mediates SARS-CoV-2 pseudovirion entry into HEK-293T cells

Abstract Background The novel coronavirus disease of 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Data from the COVID-19 clinical control case studies showed that this disease could also manifest in patients with underlying microbia...

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Bibliographic Details
Main Authors: Nozethu Mjokane, Eric O. Akintemi, Saheed Sabiu, Onele M. N. Gcilitshana, Jacobus Albertyn, Carolina H. Pohl, Olihile M. Sebolai
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Virology Journal
Subjects:
Aspergillus (A) fumigatus
A. Fumigatus alkaline protease 1
Haddock
HEK-293T cells
SARS-CoV-2 spike protein
Supernatant
Online Access:https://doi.org/10.1186/s12985-024-02331-z

Internet

https://doi.org/10.1186/s12985-024-02331-z

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