Neural Networks Recapitulation by Cancer Cells Promotes Disease Progression: A Novel Role of p73 Isoforms in Cancer-Neuronal Crosstalk

Neural Networks Recapitulation by Cancer Cells Promotes Disease Progression: A Novel Role of p73 Isoforms in Cancer-Neuronal Crosstalk

Mechanisms governing tumor progression differ from those of initiation. One enigmatic prometastatic process is the recapitulation of pathways of neural plasticity in aggressive stages. Cancer and neuronal cells develop reciprocal interactions via mutual production and secretion of neuronal growth fa...

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Bibliographic Details
Main Authors: Stella Logotheti, Stephan Marquardt, Christin Richter, Renée Sophie Hain, Nico Murr, Işıl Takan, Athanasia Pavlopoulou, Brigitte M. Pützer
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
cancer–neural crosstalk
neoneurogenesis
perineural invasion
metastasis
melanoma
p73
Online Access:https://www.mdpi.com/2072-6694/12/12/3789

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