Combatting Fusarium head blight: advances in molecular interactions between Fusarium graminearum and wheat
Abstract Fusarium head blight (FHB), mainly caused by Fusarium graminearum, is one of the most devastating diseases in wheat and barley worldwide. In addition to causing severe yield losses, F. graminearum produces deoxynivalenol (DON), a trichothecene mycotoxin which is harmful to human health and...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-10-01
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| Series: | Phytopathology Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s42483-022-00142-0 |
| _version_ | 1811182128286662656 |
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| author | Ming Xu Qinhu Wang Guanghui Wang Xue Zhang Huiquan Liu Cong Jiang |
| author_facet | Ming Xu Qinhu Wang Guanghui Wang Xue Zhang Huiquan Liu Cong Jiang |
| author_sort | Ming Xu |
| collection | DOAJ |
| description | Abstract Fusarium head blight (FHB), mainly caused by Fusarium graminearum, is one of the most devastating diseases in wheat and barley worldwide. In addition to causing severe yield losses, F. graminearum produces deoxynivalenol (DON), a trichothecene mycotoxin which is harmful to human health and serves as an important virulence factor. Currently, changes in global climate and tillage systems have made FHB epidemics more frequent and severe. During the past decade, considerable efforts have been deployed to reveal the pathogenic mechanisms of F. graminearum, identify resistance genes in wheat, and breed FHB-resistant varieties. In this review, we highlight recent advances in FHB pathogenesis, F. graminearum-wheat interaction, and wheat defense mechanisms. This review contains four main sections: (1) signal sensing and transduction associated with the pathogenesis of F. graminearum; (2) regulation and functions of DON during wheat infection; (3) roles of F. graminearum-secreted enzymes and effectors in facilitating pathogen infection of wheat; (4) wheat components involved in interactions with F. graminearum. A comprehensive understanding of the molecular interactions between F. graminearum and wheat will contribute to the development of novel and efficient strategies for controlling FHB. |
| first_indexed | 2024-04-11T09:27:58Z |
| format | Article |
| id | doaj.art-77a6f68182ab463192a73ffc860e340a |
| institution | Directory Open Access Journal |
| issn | 2524-4167 |
| language | English |
| last_indexed | 2024-04-11T09:27:58Z |
| publishDate | 2022-10-01 |
| publisher | BMC |
| record_format | Article |
| series | Phytopathology Research |
| spelling | doaj.art-77a6f68182ab463192a73ffc860e340a2022-12-22T04:31:58ZengBMCPhytopathology Research2524-41672022-10-014111610.1186/s42483-022-00142-0Combatting Fusarium head blight: advances in molecular interactions between Fusarium graminearum and wheatMing Xu0Qinhu Wang1Guanghui Wang2Xue Zhang3Huiquan Liu4Cong Jiang5State Key Laboratory of Crop Stress Biology for Arid Areas and NWAFU-Purdue Joint Research Center, College of Plant Protection, Northwest A&F UniversityState Key Laboratory of Crop Stress Biology for Arid Areas and NWAFU-Purdue Joint Research Center, College of Plant Protection, Northwest A&F UniversityState Key Laboratory of Crop Stress Biology for Arid Areas and NWAFU-Purdue Joint Research Center, College of Plant Protection, Northwest A&F UniversityState Key Laboratory of Crop Stress Biology for Arid Areas and NWAFU-Purdue Joint Research Center, College of Plant Protection, Northwest A&F UniversityState Key Laboratory of Crop Stress Biology for Arid Areas and NWAFU-Purdue Joint Research Center, College of Plant Protection, Northwest A&F UniversityState Key Laboratory of Crop Stress Biology for Arid Areas and NWAFU-Purdue Joint Research Center, College of Plant Protection, Northwest A&F UniversityAbstract Fusarium head blight (FHB), mainly caused by Fusarium graminearum, is one of the most devastating diseases in wheat and barley worldwide. In addition to causing severe yield losses, F. graminearum produces deoxynivalenol (DON), a trichothecene mycotoxin which is harmful to human health and serves as an important virulence factor. Currently, changes in global climate and tillage systems have made FHB epidemics more frequent and severe. During the past decade, considerable efforts have been deployed to reveal the pathogenic mechanisms of F. graminearum, identify resistance genes in wheat, and breed FHB-resistant varieties. In this review, we highlight recent advances in FHB pathogenesis, F. graminearum-wheat interaction, and wheat defense mechanisms. This review contains four main sections: (1) signal sensing and transduction associated with the pathogenesis of F. graminearum; (2) regulation and functions of DON during wheat infection; (3) roles of F. graminearum-secreted enzymes and effectors in facilitating pathogen infection of wheat; (4) wheat components involved in interactions with F. graminearum. A comprehensive understanding of the molecular interactions between F. graminearum and wheat will contribute to the development of novel and efficient strategies for controlling FHB.https://doi.org/10.1186/s42483-022-00142-0FHBSignaling pathwayVirulence factorDONEffectorDisease resistance |
| spellingShingle | Ming Xu Qinhu Wang Guanghui Wang Xue Zhang Huiquan Liu Cong Jiang Combatting Fusarium head blight: advances in molecular interactions between Fusarium graminearum and wheat Phytopathology Research FHB Signaling pathway Virulence factor DON Effector Disease resistance |
| title | Combatting Fusarium head blight: advances in molecular interactions between Fusarium graminearum and wheat |
| title_full | Combatting Fusarium head blight: advances in molecular interactions between Fusarium graminearum and wheat |
| title_fullStr | Combatting Fusarium head blight: advances in molecular interactions between Fusarium graminearum and wheat |
| title_full_unstemmed | Combatting Fusarium head blight: advances in molecular interactions between Fusarium graminearum and wheat |
| title_short | Combatting Fusarium head blight: advances in molecular interactions between Fusarium graminearum and wheat |
| title_sort | combatting fusarium head blight advances in molecular interactions between fusarium graminearum and wheat |
| topic | FHB Signaling pathway Virulence factor DON Effector Disease resistance |
| url | https://doi.org/10.1186/s42483-022-00142-0 |
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