An environmentally benign, simple and proficient synthesis of quinoline derivatives catalyzed by FeCl3.6H2O as a green and readily available catalyst
We report here a facile, one-pot, environmentally friendly, and efficient protocol for the synthesis of quinoline derivatives from the condensation of 2-aminoarylketones and active methylene compounds catalyzed by inexpensive, nontoxic and environmentally benign FeCl3.6H2O catalyst. The results obta...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2021-01-01
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| Series: | Green Chemistry Letters and Reviews |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/17518253.2020.1869840 |
| _version_ | 1818368709604933632 |
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| author | S. Tasqeeruddin Yahya I. Asiri S. Shaheen |
| author_facet | S. Tasqeeruddin Yahya I. Asiri S. Shaheen |
| author_sort | S. Tasqeeruddin |
| collection | DOAJ |
| description | We report here a facile, one-pot, environmentally friendly, and efficient protocol for the synthesis of quinoline derivatives from the condensation of 2-aminoarylketones and active methylene compounds catalyzed by inexpensive, nontoxic and environmentally benign FeCl3.6H2O catalyst. The results obtained by using FeCl3.6H2O catalyst were also compared with those described in the literature. This methodology offers several advantages such as shorter reaction time, milder conditions, easy workup, and better yields. The non-extractive workup/purification, economic and environmentally benign catalyst make this operationally straightforward procedure affordable for a large scale. |
| first_indexed | 2024-12-13T23:12:16Z |
| format | Article |
| id | doaj.art-77a9337ec3594e73a54eefdf48e5c659 |
| institution | Directory Open Access Journal |
| issn | 1751-8253 1751-7192 |
| language | English |
| last_indexed | 2024-12-13T23:12:16Z |
| publishDate | 2021-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Green Chemistry Letters and Reviews |
| spelling | doaj.art-77a9337ec3594e73a54eefdf48e5c6592022-12-21T23:28:03ZengTaylor & Francis GroupGreen Chemistry Letters and Reviews1751-82531751-71922021-01-0114111912710.1080/17518253.2020.18698401869840An environmentally benign, simple and proficient synthesis of quinoline derivatives catalyzed by FeCl3.6H2O as a green and readily available catalystS. Tasqeeruddin0Yahya I. Asiri1S. Shaheen2King Khalid UniversityKing Khalid UniversityAnwarul Uloom College of PharmacyWe report here a facile, one-pot, environmentally friendly, and efficient protocol for the synthesis of quinoline derivatives from the condensation of 2-aminoarylketones and active methylene compounds catalyzed by inexpensive, nontoxic and environmentally benign FeCl3.6H2O catalyst. The results obtained by using FeCl3.6H2O catalyst were also compared with those described in the literature. This methodology offers several advantages such as shorter reaction time, milder conditions, easy workup, and better yields. The non-extractive workup/purification, economic and environmentally benign catalyst make this operationally straightforward procedure affordable for a large scale.http://dx.doi.org/10.1080/17518253.2020.1869840an environmentally benign fecl3.6h2o catalystsubstituted 2-arylketonesactive methylene diketonesgreen synthesis |
| spellingShingle | S. Tasqeeruddin Yahya I. Asiri S. Shaheen An environmentally benign, simple and proficient synthesis of quinoline derivatives catalyzed by FeCl3.6H2O as a green and readily available catalyst Green Chemistry Letters and Reviews an environmentally benign fecl3.6h2o catalyst substituted 2-arylketones active methylene diketones green synthesis |
| title | An environmentally benign, simple and proficient synthesis of quinoline derivatives catalyzed by FeCl3.6H2O as a green and readily available catalyst |
| title_full | An environmentally benign, simple and proficient synthesis of quinoline derivatives catalyzed by FeCl3.6H2O as a green and readily available catalyst |
| title_fullStr | An environmentally benign, simple and proficient synthesis of quinoline derivatives catalyzed by FeCl3.6H2O as a green and readily available catalyst |
| title_full_unstemmed | An environmentally benign, simple and proficient synthesis of quinoline derivatives catalyzed by FeCl3.6H2O as a green and readily available catalyst |
| title_short | An environmentally benign, simple and proficient synthesis of quinoline derivatives catalyzed by FeCl3.6H2O as a green and readily available catalyst |
| title_sort | environmentally benign simple and proficient synthesis of quinoline derivatives catalyzed by fecl3 6h2o as a green and readily available catalyst |
| topic | an environmentally benign fecl3.6h2o catalyst substituted 2-arylketones active methylene diketones green synthesis |
| url | http://dx.doi.org/10.1080/17518253.2020.1869840 |
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