Beam neutron energy optimization for boron neutron capture therapy using Monte Carlo method
In last two decades the optimal neutron energy for the treatment of deep seated tumors in boron neutron capture therapy in view of neutron physics and chemical compounds of boron carrier has been under thorough study. Although neutron absorption cross section of boron is high (3836b), the treatment...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Isfahan University of Technology
2006-06-01
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| Series: | Iranian Journal of Physics Research |
| Subjects: | |
| Online Access: | http://ijpr.iut.ac.ir/browse.php?a_code=A-10-1-40&slc_lang=en&sid=1 |
| _version_ | 1818514799904948224 |
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| author | Ali Pazirandeh Elham Shekarian |
| author_facet | Ali Pazirandeh Elham Shekarian |
| author_sort | Ali Pazirandeh |
| collection | DOAJ |
| description | In last two decades the optimal neutron energy for the treatment of deep seated tumors in boron neutron capture therapy in view of neutron physics and chemical compounds of boron carrier has been under thorough study. Although neutron absorption cross section of boron is high (3836b), the treatment of deep seated tumors such as gliobelastoma multiform (GBM) requires beam of neutrons of higher energy that can penetrate deeply into the brain and thermalize in the proximity of the tumor. Dosage from recoil proton associated with fast neutrons however poses some constraints on maximum neutron energy that can be used in the treatment. For this reason neutrons in the epithermal energy range of 10eV-10keV are generally to be the most appropriate. The simulation carried out by Monte Carlo methods using MCBNCT and MCNP4C codes along with the cross section library in 290 groups extracted from ENDF/B6 main library. The optimal neutron energy for deep seated tumors depends on the size and depth of tumor. Our estimated optimized energy for the tumor of 5cm wide and 1-2cm thick stands at 5cm depth is in the range of 3-5keV |
| first_indexed | 2024-12-11T00:20:42Z |
| format | Article |
| id | doaj.art-77b096346e5c4bbd8de368788a2ecae8 |
| institution | Directory Open Access Journal |
| issn | 1682-6957 |
| language | English |
| last_indexed | 2024-12-11T00:20:42Z |
| publishDate | 2006-06-01 |
| publisher | Isfahan University of Technology |
| record_format | Article |
| series | Iranian Journal of Physics Research |
| spelling | doaj.art-77b096346e5c4bbd8de368788a2ecae82022-12-22T01:27:45ZengIsfahan University of TechnologyIranian Journal of Physics Research1682-69572006-06-01625565Beam neutron energy optimization for boron neutron capture therapy using Monte Carlo methodAli PazirandehElham ShekarianIn last two decades the optimal neutron energy for the treatment of deep seated tumors in boron neutron capture therapy in view of neutron physics and chemical compounds of boron carrier has been under thorough study. Although neutron absorption cross section of boron is high (3836b), the treatment of deep seated tumors such as gliobelastoma multiform (GBM) requires beam of neutrons of higher energy that can penetrate deeply into the brain and thermalize in the proximity of the tumor. Dosage from recoil proton associated with fast neutrons however poses some constraints on maximum neutron energy that can be used in the treatment. For this reason neutrons in the epithermal energy range of 10eV-10keV are generally to be the most appropriate. The simulation carried out by Monte Carlo methods using MCBNCT and MCNP4C codes along with the cross section library in 290 groups extracted from ENDF/B6 main library. The optimal neutron energy for deep seated tumors depends on the size and depth of tumor. Our estimated optimized energy for the tumor of 5cm wide and 1-2cm thick stands at 5cm depth is in the range of 3-5keVhttp://ijpr.iut.ac.ir/browse.php?a_code=A-10-1-40&slc_lang=en&sid=1BNCTepithermal neutrontumorMonte Carlogliobelastomakerma |
| spellingShingle | Ali Pazirandeh Elham Shekarian Beam neutron energy optimization for boron neutron capture therapy using Monte Carlo method Iranian Journal of Physics Research BNCT epithermal neutron tumor Monte Carlo gliobelastoma kerma |
| title | Beam neutron energy optimization for boron neutron capture therapy using Monte Carlo method |
| title_full | Beam neutron energy optimization for boron neutron capture therapy using Monte Carlo method |
| title_fullStr | Beam neutron energy optimization for boron neutron capture therapy using Monte Carlo method |
| title_full_unstemmed | Beam neutron energy optimization for boron neutron capture therapy using Monte Carlo method |
| title_short | Beam neutron energy optimization for boron neutron capture therapy using Monte Carlo method |
| title_sort | beam neutron energy optimization for boron neutron capture therapy using monte carlo method |
| topic | BNCT epithermal neutron tumor Monte Carlo gliobelastoma kerma |
| url | http://ijpr.iut.ac.ir/browse.php?a_code=A-10-1-40&slc_lang=en&sid=1 |
| work_keys_str_mv | AT alipazirandeh beamneutronenergyoptimizationforboronneutroncapturetherapyusingmontecarlomethod AT elhamshekarian beamneutronenergyoptimizationforboronneutroncapturetherapyusingmontecarlomethod |