Ambient fine particulate matter exposure induces reversible cardiac dysfunction and fibrosis in juvenile and older female mice

Ambient fine particulate matter exposure induces reversible cardiac dysfunction and fibrosis in juvenile and older female mice

Abstract Background Cardiovascular disease is the leading cause of mortality in the advanced world, and age is an important determinant of cardiac function. The purpose of the study is to determine whether the PM2.5-induced cardiac dysfunction is age-dependent and whether the adverse effects can be...

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Bibliographic Details
Main Authors: Guohua Qin, Jin Xia, Yingying Zhang, Lianghong Guo, Rui Chen, Nan Sang
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Particle and Fibre Toxicology
Subjects:
Particulate matter
Cardiac
Fibrosis
Reversible
Different age
Online Access:http://link.springer.com/article/10.1186/s12989-018-0264-2

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