The Role of Kynurenine and Its Metabolites in Comorbid Chronic Pain and Depression

The Role of Kynurenine and Its Metabolites in Comorbid Chronic Pain and Depression

Chronic pain and depression affect millions of people worldwide, and their comorbidity tends to exacerbate the severity of each individual condition. Intersecting brain regions and molecular pathways could probably explain the unique yet complex bidirectional relationship between these two disorders...

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Bibliographic Details
Main Authors: Onella Athnaiel, Charmaine Ong, Nebojsa Nick Knezevic
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Metabolites
Subjects:
depression
chronic pain
kynurenine pathway
quinolinic acid
kynurenic acid
inflammation
Online Access:https://www.mdpi.com/2218-1989/12/10/950

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