Association between hypoalbuminemia and hypophosphatemia with malnutrition in patients with chronic renal disease undergoing hemodialysis
Introduction: Malnutrition in hemodialysis patients is a consequence of various deficiency andhypercatabolic factors and constitutes a risk factor for morbidity and mortality. Objective: Determinethe association between hypoalbuminemia and hypophosphatemia with the Subjective globalassessment (SGA)...
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| Format: | Article |
| Language: | Spanish |
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Universidad Ricardo Palma
2020-07-01
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| Series: | Revista de la Facultad de Medicina Humana |
| Subjects: | |
| Online Access: | http://revistas.urp.edu.pe/index.php/RFMH/article/view/2968 |
| _version_ | 1818566420366098432 |
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| author | Edwin Castillo Velarde Gloria Montero Pacora Sandra García Llajaruna |
| author_facet | Edwin Castillo Velarde Gloria Montero Pacora Sandra García Llajaruna |
| author_sort | Edwin Castillo Velarde |
| collection | DOAJ |
| description | Introduction: Malnutrition in hemodialysis patients is a consequence of various deficiency andhypercatabolic factors and constitutes a risk factor for morbidity and mortality. Objective: Determinethe association between hypoalbuminemia and hypophosphatemia with the Subjective globalassessment (SGA) C in patients with chronic renal disease on hemodialysis. Methods: Analytical cross-sectional study. Patients from the hemodialysis service of the Hospital Guillermo Almenara werestudied. The Kruskal-Wallis test and multiple comparisons test were used for the association betweencontinuous variables of malnutrition and the types of SGA. The square-chi test was used for thecategorical variables hypoalbuminemia (≤3.5 g/dL) and hypophosphatemia (<3 mg/dL). The associationwith SGA C was analyzed. Results: 131 patients were included and the median age was 63 years. 34%had hypoalbuminemia, 27% had hypophosphatemia and 14% had SGA C. 52% (68) of the patientspresented alteration of at least one analyzed biomarker. Differences were found between SGA andalbumin (p<0.001) and phosphorus (p=0.040). Patients with SGA C had a mean albumin of 3.1±0.74 andphosphorus of 2.88±1.54 and had a significant difference compared to those with SGA A (p<0.001 and P= 0.011, respectively). Chi-square analysis also demonstrated a significant association between SGA andhypoalbuminemia (p = 0.017) and hypophosphatemia (p=0.050). Conclusion: There is an associationbetween SGA C and hypoalbuminemia and hypophosphatemia in patients with chronic kidney diseaseundergoing hemodialysis. |
| first_indexed | 2024-12-14T01:53:30Z |
| format | Article |
| id | doaj.art-77b8a187365e485a87574f938f9fcdb2 |
| institution | Directory Open Access Journal |
| issn | 1814-5469 2308-0531 |
| language | Spanish |
| last_indexed | 2024-12-14T01:53:30Z |
| publishDate | 2020-07-01 |
| publisher | Universidad Ricardo Palma |
| record_format | Article |
| series | Revista de la Facultad de Medicina Humana |
| spelling | doaj.art-77b8a187365e485a87574f938f9fcdb22022-12-21T23:21:18ZspaUniversidad Ricardo PalmaRevista de la Facultad de Medicina Humana1814-54692308-05312020-07-0120338138710.25176/RFMH.v20i3.2968Association between hypoalbuminemia and hypophosphatemia with malnutrition in patients with chronic renal disease undergoing hemodialysisEdwin Castillo Velardehttps://orcid.org/0000-0001-7532-1237Gloria Montero Pacorahttps://orcid.org/0000-0002-7312-0404Sandra García Llajarunahttps://orcid.org/0000-0002-3084-7101Introduction: Malnutrition in hemodialysis patients is a consequence of various deficiency andhypercatabolic factors and constitutes a risk factor for morbidity and mortality. Objective: Determinethe association between hypoalbuminemia and hypophosphatemia with the Subjective globalassessment (SGA) C in patients with chronic renal disease on hemodialysis. Methods: Analytical cross-sectional study. Patients from the hemodialysis service of the Hospital Guillermo Almenara werestudied. The Kruskal-Wallis test and multiple comparisons test were used for the association betweencontinuous variables of malnutrition and the types of SGA. The square-chi test was used for thecategorical variables hypoalbuminemia (≤3.5 g/dL) and hypophosphatemia (<3 mg/dL). The associationwith SGA C was analyzed. Results: 131 patients were included and the median age was 63 years. 34%had hypoalbuminemia, 27% had hypophosphatemia and 14% had SGA C. 52% (68) of the patientspresented alteration of at least one analyzed biomarker. Differences were found between SGA andalbumin (p<0.001) and phosphorus (p=0.040). Patients with SGA C had a mean albumin of 3.1±0.74 andphosphorus of 2.88±1.54 and had a significant difference compared to those with SGA A (p<0.001 and P= 0.011, respectively). Chi-square analysis also demonstrated a significant association between SGA andhypoalbuminemia (p = 0.017) and hypophosphatemia (p=0.050). Conclusion: There is an associationbetween SGA C and hypoalbuminemia and hypophosphatemia in patients with chronic kidney diseaseundergoing hemodialysis.http://revistas.urp.edu.pe/index.php/RFMH/article/view/2968hypoalbuminemiahypophosphatemiamalnutritiondialysis |
| spellingShingle | Edwin Castillo Velarde Gloria Montero Pacora Sandra García Llajaruna Association between hypoalbuminemia and hypophosphatemia with malnutrition in patients with chronic renal disease undergoing hemodialysis Revista de la Facultad de Medicina Humana hypoalbuminemia hypophosphatemia malnutrition dialysis |
| title | Association between hypoalbuminemia and hypophosphatemia with malnutrition in patients with chronic renal disease undergoing hemodialysis |
| title_full | Association between hypoalbuminemia and hypophosphatemia with malnutrition in patients with chronic renal disease undergoing hemodialysis |
| title_fullStr | Association between hypoalbuminemia and hypophosphatemia with malnutrition in patients with chronic renal disease undergoing hemodialysis |
| title_full_unstemmed | Association between hypoalbuminemia and hypophosphatemia with malnutrition in patients with chronic renal disease undergoing hemodialysis |
| title_short | Association between hypoalbuminemia and hypophosphatemia with malnutrition in patients with chronic renal disease undergoing hemodialysis |
| title_sort | association between hypoalbuminemia and hypophosphatemia with malnutrition in patients with chronic renal disease undergoing hemodialysis |
| topic | hypoalbuminemia hypophosphatemia malnutrition dialysis |
| url | http://revistas.urp.edu.pe/index.php/RFMH/article/view/2968 |
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