Fallopian tube secreted protein affects ovarian metabolites in high grade serous ovarian cancer

Fallopian tube secreted protein affects ovarian metabolites in high grade serous ovarian cancer

High grade serous ovarian cancer (HGSOC), the most lethal histotype of ovarian cancer, frequently arises from fallopian tube epithelial cells (FTE). Once transformed, tumorigenic FTE often migrate specifically to the ovary, completing the crucial primary metastatic step and allowing the formation of...

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Bibliographic Details
Main Authors: Tova M. Bergsten, Sarah E. Levy, Katherine E. Zink, Hannah J. Lusk, Melissa R. Pergande, Stephanie M. Cologna, Joanna E. Burdette, Laura M. Sanchez
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
ovarian cancer
imaging mass spectrometry (IMS)
fallopian tube
tumor micro environment
proteomics
SPARC
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.1042734/full

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