High fat diet induces microbiota-dependent silencing of enteroendocrine cells

High fat diet induces microbiota-dependent silencing of enteroendocrine cells

Enteroendocrine cells (EECs) are specialized sensory cells in the intestinal epithelium that sense and transduce nutrient information. Consumption of dietary fat contributes to metabolic disorders, but EEC adaptations to high fat feeding were unknown. Here, we established a new experimental system t...

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Bibliographic Details
Main Authors: Lihua Ye, Olaf Mueller, Jennifer Bagwell, Michel Bagnat, Rodger A Liddle, John F Rawls
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-12-01
Series:eLife
Subjects:
enteroendocrine cells
microbiome
Danio rerio
zebrafish
Acinetobacter
digestive physiology
Online Access:https://elifesciences.org/articles/48479

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