Immune checkpoint inhibitor-induced hypothyroidism predicts treatment response in Japanese subjects

Immune checkpoint inhibitor-induced hypothyroidism predicts treatment response in Japanese subjects

BackgroundImmune checkpoint inhibitors (ICIs) cause a variety of immune-related adverse events (irAEs). Among them, thyroid dysfunction is most frequently observed. Patients with irAEs have higher survival rates than those without irAEs, but there is no certainty as to whether the degree of thyroid...

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Bibliographic Details
Main Authors: Yuichiro Iwamoto, Tomohiko Kimura, Kazunori Dan, Mana Ohnishi, Haruka Takenouchi, Hideyuki Iwamoto, Junpei Sanada, Yoshiro Fushimi, Yukino Katakura, Masashi Shimoda, Shuhei Nakanishi, Tomoatsu Mune, Kohei Kaku, Hideaki Kaneto
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Endocrinology
Subjects:
immune-related adverse events
immune check point inhibitors
hypothyroidism
transient thyrotoxicosis
retrospective study
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1221723/full

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