Analisis Scanning Electron Microscope (SEM) Mikroarsitektur Daerah Metafisis Os Femur Tikus Putih (Rattus novergicus) Ovariohisterektomi dengan Pemberian Madu Lebah (Apis dorsata) Hutan Sumbawa
The aims of this study to determine the effect of honey bees (Apis dorsata) to prevent the decrease of femur density in ovariohysterctomized rats as animal model of osteoporosis by Scanning Electron Microscope (SEM). This study used 20 adult female white rats (Rattus norvegicus) with body weight 30...
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| Format: | Article |
| Language: | Indonesian |
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Universitas Gadjah Mada
2018-10-01
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| Series: | Jurnal Sain Veteriner |
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| Online Access: | https://jurnal.ugm.ac.id/jsv/article/view/38446 |
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| author | Samsi Yordan Abdullah Hasib Muhammad Huda Ramadhan Ibrahim Siti Nur Rohmah Salsabilla Abani Ira Sari Yudaniayanti |
| author_facet | Samsi Yordan Abdullah Hasib Muhammad Huda Ramadhan Ibrahim Siti Nur Rohmah Salsabilla Abani Ira Sari Yudaniayanti |
| author_sort | Samsi Yordan |
| collection | DOAJ |
| description | The aims of this study to determine the effect of honey bees (Apis dorsata) to prevent the decrease of femur density in ovariohysterctomized rats as animal model of osteoporosis by Scanning Electron Microscope (SEM). This study used 20 adult female white rats (Rattus norvegicus) with body weight 300 gr. Divided into 5 groups, negative control group (P0-), not in ovariohysterectomy, only given aquadest 1.5 ml/day ; Positive control group (P0 +), in ovariohysterectomy, only given aquadest 1.5 ml/day; Treatment group 1 (P1), in ovariohysterectomy and given honey 1 gram / kg BB + 1.5 ml aquadest; Treatment group 2 (P2), in ovariohysterectomy and given honey 2 grams / kg BB + 1.5 ml aquadest; Treatment group 3 (P3), in ovariohysterectomy and given honey 4 grams / kg BB + 1.5 ml aquadest. After 12 weeks, all rats were sacrified for removal of the femur and performed by SEM. Analysis of SEM showed that mice administered honey with a dose of 4 grams / kg BW (P3) showed bone density approaching negative control treatment (P0-), ie, ovariohysterectomized rats. P3 showed the most less bone porosity than other treatment groups. The largest and most uniformly distributed porosity was shown by the positive control group (P0 +). The best results with the smallest quantity and size of the porosity of femur is in P3 group. In conclusion, honey (Apis dorsata) can prevent the decrease in bone density of the femur by Scanning Electron Microscope (SEM). |
| first_indexed | 2024-04-14T01:55:23Z |
| format | Article |
| id | doaj.art-77c8fa74df134178863f3d1c4a23e758 |
| institution | Directory Open Access Journal |
| issn | 0126-0421 2407-3733 |
| language | Indonesian |
| last_indexed | 2024-04-14T01:55:23Z |
| publishDate | 2018-10-01 |
| publisher | Universitas Gadjah Mada |
| record_format | Article |
| series | Jurnal Sain Veteriner |
| spelling | doaj.art-77c8fa74df134178863f3d1c4a23e7582022-12-22T02:19:07ZindUniversitas Gadjah MadaJurnal Sain Veteriner0126-04212407-37332018-10-01361586510.22146/jsv.3844621889Analisis Scanning Electron Microscope (SEM) Mikroarsitektur Daerah Metafisis Os Femur Tikus Putih (Rattus novergicus) Ovariohisterektomi dengan Pemberian Madu Lebah (Apis dorsata) Hutan SumbawaSamsi Yordan0Abdullah Hasib1Muhammad Huda Ramadhan Ibrahim2Siti Nur Rohmah3Salsabilla Abani4Ira Sari Yudaniayanti5Fakultas Kedokteran Hewan Universitas Airlangga, SurabayaFakultas Kedokteran Hewan Universitas Airlangga, SurabayaFakultas Kedokteran Hewan Universitas Airlangga, SurabayaFakultas Kedokteran Hewan Universitas Airlangga, SurabayaFakultas Kedokteran Hewan Universitas Airlangga, SurabayaFakultas Kedokteran Hewan Universitas Airlangga, SurabayaThe aims of this study to determine the effect of honey bees (Apis dorsata) to prevent the decrease of femur density in ovariohysterctomized rats as animal model of osteoporosis by Scanning Electron Microscope (SEM). This study used 20 adult female white rats (Rattus norvegicus) with body weight 300 gr. Divided into 5 groups, negative control group (P0-), not in ovariohysterectomy, only given aquadest 1.5 ml/day ; Positive control group (P0 +), in ovariohysterectomy, only given aquadest 1.5 ml/day; Treatment group 1 (P1), in ovariohysterectomy and given honey 1 gram / kg BB + 1.5 ml aquadest; Treatment group 2 (P2), in ovariohysterectomy and given honey 2 grams / kg BB + 1.5 ml aquadest; Treatment group 3 (P3), in ovariohysterectomy and given honey 4 grams / kg BB + 1.5 ml aquadest. After 12 weeks, all rats were sacrified for removal of the femur and performed by SEM. Analysis of SEM showed that mice administered honey with a dose of 4 grams / kg BW (P3) showed bone density approaching negative control treatment (P0-), ie, ovariohysterectomized rats. P3 showed the most less bone porosity than other treatment groups. The largest and most uniformly distributed porosity was shown by the positive control group (P0 +). The best results with the smallest quantity and size of the porosity of femur is in P3 group. In conclusion, honey (Apis dorsata) can prevent the decrease in bone density of the femur by Scanning Electron Microscope (SEM).https://jurnal.ugm.ac.id/jsv/article/view/38446HoneyOsteoporosisScanning Electron Microscope |
| spellingShingle | Samsi Yordan Abdullah Hasib Muhammad Huda Ramadhan Ibrahim Siti Nur Rohmah Salsabilla Abani Ira Sari Yudaniayanti Analisis Scanning Electron Microscope (SEM) Mikroarsitektur Daerah Metafisis Os Femur Tikus Putih (Rattus novergicus) Ovariohisterektomi dengan Pemberian Madu Lebah (Apis dorsata) Hutan Sumbawa Jurnal Sain Veteriner Honey Osteoporosis Scanning Electron Microscope |
| title | Analisis Scanning Electron Microscope (SEM) Mikroarsitektur Daerah Metafisis Os Femur Tikus Putih (Rattus novergicus) Ovariohisterektomi dengan Pemberian Madu Lebah (Apis dorsata) Hutan Sumbawa |
| title_full | Analisis Scanning Electron Microscope (SEM) Mikroarsitektur Daerah Metafisis Os Femur Tikus Putih (Rattus novergicus) Ovariohisterektomi dengan Pemberian Madu Lebah (Apis dorsata) Hutan Sumbawa |
| title_fullStr | Analisis Scanning Electron Microscope (SEM) Mikroarsitektur Daerah Metafisis Os Femur Tikus Putih (Rattus novergicus) Ovariohisterektomi dengan Pemberian Madu Lebah (Apis dorsata) Hutan Sumbawa |
| title_full_unstemmed | Analisis Scanning Electron Microscope (SEM) Mikroarsitektur Daerah Metafisis Os Femur Tikus Putih (Rattus novergicus) Ovariohisterektomi dengan Pemberian Madu Lebah (Apis dorsata) Hutan Sumbawa |
| title_short | Analisis Scanning Electron Microscope (SEM) Mikroarsitektur Daerah Metafisis Os Femur Tikus Putih (Rattus novergicus) Ovariohisterektomi dengan Pemberian Madu Lebah (Apis dorsata) Hutan Sumbawa |
| title_sort | analisis scanning electron microscope sem mikroarsitektur daerah metafisis os femur tikus putih rattus novergicus ovariohisterektomi dengan pemberian madu lebah apis dorsata hutan sumbawa |
| topic | Honey Osteoporosis Scanning Electron Microscope |
| url | https://jurnal.ugm.ac.id/jsv/article/view/38446 |
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