Design and Fabrication of a MEMS Flow Sensor and Its Application in Precise Liquid Dispensing

A high speed MEMS flow sensor to enhance the reliability and accuracy of a liquid dispensing system is proposed. Benefitting from the sensor information feedback, the system can self-adjust the open time of the solenoid valve to accurately dispense desired volumes of reagent without any pre-calibrat...

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Main Authors: Liguo Chen, Yaxin Liu, Lining Sun
Format: Article
Language:English
Published: MDPI AG 2009-06-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/9/6/4138/
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author Liguo Chen
Yaxin Liu
Lining Sun
author_facet Liguo Chen
Yaxin Liu
Lining Sun
author_sort Liguo Chen
collection DOAJ
description A high speed MEMS flow sensor to enhance the reliability and accuracy of a liquid dispensing system is proposed. Benefitting from the sensor information feedback, the system can self-adjust the open time of the solenoid valve to accurately dispense desired volumes of reagent without any pre-calibration. First, an integrated high-speed liquid flow sensor based on the measurement of the pressure difference across a flow channel is presented. Dimensions of the micro-flow channel and two pressure sensors have been appropriately designed to meet the static and dynamic requirements of the liquid dispensing system. Experiments results show that the full scale (FS) flow measurement ranges up to 80 μL/s, with a nonlinearity better than 0.51% FS. Secondly, a novel closed-loop control strategy is proposed to calculate the valve open time in each dispensing cycle, which makes the system immune to liquid viscosity, pressure fluctuation, and other sources of error. Finally, dispensing results show that the system can achieve better dispensing performance, and the coefficient of variance (CV) for liquid dispensing is below 3% at 1 μL and below 4% at 100 nL.
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spelling doaj.art-77cecf0ea4144eb98624da0e6e052daf2022-12-22T04:25:17ZengMDPI AGSensors1424-82202009-06-01964138415010.3390/s90604138Design and Fabrication of a MEMS Flow Sensor and Its Application in Precise Liquid DispensingLiguo ChenYaxin LiuLining SunA high speed MEMS flow sensor to enhance the reliability and accuracy of a liquid dispensing system is proposed. Benefitting from the sensor information feedback, the system can self-adjust the open time of the solenoid valve to accurately dispense desired volumes of reagent without any pre-calibration. First, an integrated high-speed liquid flow sensor based on the measurement of the pressure difference across a flow channel is presented. Dimensions of the micro-flow channel and two pressure sensors have been appropriately designed to meet the static and dynamic requirements of the liquid dispensing system. Experiments results show that the full scale (FS) flow measurement ranges up to 80 μL/s, with a nonlinearity better than 0.51% FS. Secondly, a novel closed-loop control strategy is proposed to calculate the valve open time in each dispensing cycle, which makes the system immune to liquid viscosity, pressure fluctuation, and other sources of error. Finally, dispensing results show that the system can achieve better dispensing performance, and the coefficient of variance (CV) for liquid dispensing is below 3% at 1 μL and below 4% at 100 nL.http://www.mdpi.com/1424-8220/9/6/4138/flow sensorMEMSliquid dispensing
spellingShingle Liguo Chen
Yaxin Liu
Lining Sun
Design and Fabrication of a MEMS Flow Sensor and Its Application in Precise Liquid Dispensing
Sensors
flow sensor
MEMS
liquid dispensing
title Design and Fabrication of a MEMS Flow Sensor and Its Application in Precise Liquid Dispensing
title_full Design and Fabrication of a MEMS Flow Sensor and Its Application in Precise Liquid Dispensing
title_fullStr Design and Fabrication of a MEMS Flow Sensor and Its Application in Precise Liquid Dispensing
title_full_unstemmed Design and Fabrication of a MEMS Flow Sensor and Its Application in Precise Liquid Dispensing
title_short Design and Fabrication of a MEMS Flow Sensor and Its Application in Precise Liquid Dispensing
title_sort design and fabrication of a mems flow sensor and its application in precise liquid dispensing
topic flow sensor
MEMS
liquid dispensing
url http://www.mdpi.com/1424-8220/9/6/4138/
work_keys_str_mv AT liguochen designandfabricationofamemsflowsensoranditsapplicationinpreciseliquiddispensing
AT yaxinliu designandfabricationofamemsflowsensoranditsapplicationinpreciseliquiddispensing
AT liningsun designandfabricationofamemsflowsensoranditsapplicationinpreciseliquiddispensing