Prevalence and concordance between the clinical and the post-mortem diagnosis of dementia in a psychogeriatric clinic
Introduction: The aim of our study is to describe the types of dementia found in a series of patients and to estimate the level of agreement between the clinical diagnosis and post-mortem diagnosis. Material and methods: We conducted a descriptive analysis of the prevalence of the types of dementia...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier España
2018-01-01
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| Series: | Neurología (English Edition) |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2173580817301542 |
| _version_ | 1818316793930842112 |
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| author | B. Grandal Leiros L.I. Pérez Méndez M.V. Zelaya Huerta L. Moreno Eguinoa F. García-Bragado T. Tuñón Álvarez J.J. Roldán Larreta |
| author_facet | B. Grandal Leiros L.I. Pérez Méndez M.V. Zelaya Huerta L. Moreno Eguinoa F. García-Bragado T. Tuñón Álvarez J.J. Roldán Larreta |
| author_sort | B. Grandal Leiros |
| collection | DOAJ |
| description | Introduction: The aim of our study is to describe the types of dementia found in a series of patients and to estimate the level of agreement between the clinical diagnosis and post-mortem diagnosis. Material and methods: We conducted a descriptive analysis of the prevalence of the types of dementia found in our series and we established the level of concordance between the clinical and the post-mortem diagnoses. The diagnosis was made based on current diagnostic criteria. Results: 114 cases were included. The most common clinical diagnoses both at a clinical and autopsy level were Alzheimer disease and mixed dementia but the prevalence was quite different. While at a clinical level, prevalence was 39% for Alzheimer disease and 18% for mixed dementia, in the autopsy level, prevalence was 22% and 34%, respectively. The agreement between the clinical and the autopsy diagnoses was 62% (95% CI, 53%-72%). Conclusions: Almost a third of our patients were not correctly diagnosed in vivo. The most common mistake was the underdiagnosis of cerebrovascular pathology. Resumen: Introducción: Describir los tipos de demencia en una serie de pacientes valorados en una clínica psicogeriátrica y estimar el grado de acuerdo entre el diagnóstico clínico y el anatomopatológico. Material y métodos: Realizamos un análisis descriptivo de la prevalencia de los tipos de demencia entre los pacientes valorados en nuestro centro y establecemos el grado de concordancia entre el diagnóstico clínico y el anatomopatológico. Los diagnósticos se establecieron en función de los criterios diagnósticos vigentes en cada momento. Resultados: Ciento catorce casos cumplieron los criterios de inclusión. Los diagnósticos más frecuentes tanto a nivel clínico como anatomopatológico fueron enfermedad de Alzheimer y demencia mixta, pero la prevalencia se invirtió pasando de un 39% y 18% a nivel clínico a un 22% y 34% a nivel anatomopatológico respectivamente. La concordancia entre el diagnóstico clínico y el anatomopatológico fue de un 62% (IC 95%: 53-72%). Conclusiones: Casi un tercio de nuestros pacientes no tenía un diagnóstico certero en vida, fundamentalmente a expensas del infradiagnóstico a nivel clínico de la enfermedad cerebrovascular. Keywords: Dementia prevalence, Dementia diagnosis accuracy, Alzheimer's disease, Cerebrovascular disease, Post-mortem diagnosis, Mixed brain pathologies, Palabras clave: Prevalencia de demencia, Fiabilidad diagnóstica en demencia, Enfermedad de Alzheimer, Enfermedad cerebrovascular, Diagnóstico post-mortem, Comorbilidad cerebral |
| first_indexed | 2024-12-13T09:27:05Z |
| format | Article |
| id | doaj.art-77d04146ec494faca88159ebe860b337 |
| institution | Directory Open Access Journal |
| issn | 2173-5808 |
| language | English |
| last_indexed | 2024-12-13T09:27:05Z |
| publishDate | 2018-01-01 |
| publisher | Elsevier España |
| record_format | Article |
| series | Neurología (English Edition) |
| spelling | doaj.art-77d04146ec494faca88159ebe860b3372022-12-21T23:52:35ZengElsevier EspañaNeurología (English Edition)2173-58082018-01-013311317Prevalence and concordance between the clinical and the post-mortem diagnosis of dementia in a psychogeriatric clinicB. Grandal Leiros0L.I. Pérez Méndez1M.V. Zelaya Huerta2L. Moreno Eguinoa3F. García-Bragado4T. Tuñón Álvarez5J.J. Roldán Larreta6Servicio de Geriatría, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Spain; Corresponding author.Unidad de Investigación, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, SpainNavarrabiomed Fundación Miguel Servet, Complejo Hospitalario de Navarra Osasunbidea, Pamplona, SpainClínica Psicogeriátrica Josefina Arregui , Alsasua, Navarra, SpainDepartamento de Anatomía Patológica, Complejo Hospitalario de Navarra Osasunbidea, Pamplona, SpainDepartamento de Anatomía Patológica, Complejo Hospitalario de Navarra Osasunbidea, Pamplona, SpainClínica Psicogeriátrica Josefina Arregui , Alsasua, Navarra, SpainIntroduction: The aim of our study is to describe the types of dementia found in a series of patients and to estimate the level of agreement between the clinical diagnosis and post-mortem diagnosis. Material and methods: We conducted a descriptive analysis of the prevalence of the types of dementia found in our series and we established the level of concordance between the clinical and the post-mortem diagnoses. The diagnosis was made based on current diagnostic criteria. Results: 114 cases were included. The most common clinical diagnoses both at a clinical and autopsy level were Alzheimer disease and mixed dementia but the prevalence was quite different. While at a clinical level, prevalence was 39% for Alzheimer disease and 18% for mixed dementia, in the autopsy level, prevalence was 22% and 34%, respectively. The agreement between the clinical and the autopsy diagnoses was 62% (95% CI, 53%-72%). Conclusions: Almost a third of our patients were not correctly diagnosed in vivo. The most common mistake was the underdiagnosis of cerebrovascular pathology. Resumen: Introducción: Describir los tipos de demencia en una serie de pacientes valorados en una clínica psicogeriátrica y estimar el grado de acuerdo entre el diagnóstico clínico y el anatomopatológico. Material y métodos: Realizamos un análisis descriptivo de la prevalencia de los tipos de demencia entre los pacientes valorados en nuestro centro y establecemos el grado de concordancia entre el diagnóstico clínico y el anatomopatológico. Los diagnósticos se establecieron en función de los criterios diagnósticos vigentes en cada momento. Resultados: Ciento catorce casos cumplieron los criterios de inclusión. Los diagnósticos más frecuentes tanto a nivel clínico como anatomopatológico fueron enfermedad de Alzheimer y demencia mixta, pero la prevalencia se invirtió pasando de un 39% y 18% a nivel clínico a un 22% y 34% a nivel anatomopatológico respectivamente. La concordancia entre el diagnóstico clínico y el anatomopatológico fue de un 62% (IC 95%: 53-72%). Conclusiones: Casi un tercio de nuestros pacientes no tenía un diagnóstico certero en vida, fundamentalmente a expensas del infradiagnóstico a nivel clínico de la enfermedad cerebrovascular. Keywords: Dementia prevalence, Dementia diagnosis accuracy, Alzheimer's disease, Cerebrovascular disease, Post-mortem diagnosis, Mixed brain pathologies, Palabras clave: Prevalencia de demencia, Fiabilidad diagnóstica en demencia, Enfermedad de Alzheimer, Enfermedad cerebrovascular, Diagnóstico post-mortem, Comorbilidad cerebralhttp://www.sciencedirect.com/science/article/pii/S2173580817301542 |
| spellingShingle | B. Grandal Leiros L.I. Pérez Méndez M.V. Zelaya Huerta L. Moreno Eguinoa F. García-Bragado T. Tuñón Álvarez J.J. Roldán Larreta Prevalence and concordance between the clinical and the post-mortem diagnosis of dementia in a psychogeriatric clinic Neurología (English Edition) |
| title | Prevalence and concordance between the clinical and the post-mortem diagnosis of dementia in a psychogeriatric clinic |
| title_full | Prevalence and concordance between the clinical and the post-mortem diagnosis of dementia in a psychogeriatric clinic |
| title_fullStr | Prevalence and concordance between the clinical and the post-mortem diagnosis of dementia in a psychogeriatric clinic |
| title_full_unstemmed | Prevalence and concordance between the clinical and the post-mortem diagnosis of dementia in a psychogeriatric clinic |
| title_short | Prevalence and concordance between the clinical and the post-mortem diagnosis of dementia in a psychogeriatric clinic |
| title_sort | prevalence and concordance between the clinical and the post mortem diagnosis of dementia in a psychogeriatric clinic |
| url | http://www.sciencedirect.com/science/article/pii/S2173580817301542 |
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