Thyrotoxic Periodic Paralysis with Thyroid Storm as the First Presentation of Graves’ disease; a Case Report

Thyrotoxic periodic paralysis is a rare endocrine emergency that manifests as acute onset muscle weakness and hypokalaemia secondary to thyrotoxicosis. It mainly occurs due to rapid and dramatic intracellular shift of potassium resulting in hypokalaemia and acute flaccid paralysis. This condition pr...

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Main Authors: Tejaswee Banavathu, Swapnil Tripathi, Pankaj Sukhadiya, Kamlesh Ahari, Durga Shankar Meena, Mahendra Kumar Garg
Format: Article
Language:English
Published: Shahid Beheshti University of Medical Sciences 2021-02-01
Series:Archives of Academic Emergency Medicine
Subjects:
Online Access:https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/1083
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author Tejaswee Banavathu
Swapnil Tripathi
Pankaj Sukhadiya
Kamlesh Ahari
Durga Shankar Meena
Mahendra Kumar Garg
author_facet Tejaswee Banavathu
Swapnil Tripathi
Pankaj Sukhadiya
Kamlesh Ahari
Durga Shankar Meena
Mahendra Kumar Garg
author_sort Tejaswee Banavathu
collection DOAJ
description Thyrotoxic periodic paralysis is a rare endocrine emergency that manifests as acute onset muscle weakness and hypokalaemia secondary to thyrotoxicosis. It mainly occurs due to rapid and dramatic intracellular shift of potassium resulting in hypokalaemia and acute flaccid paralysis. This condition predominantly affects males of Asian descent, and presentation can range from mild generalized weakness to complete quadriplegia, as seen in our case. We herein report a case of a 40-year-old female, who presented to us with acute onset flaccid quadriplegia and thyroid storm, which is the first ever manifestation of previously undiagnosed Grave’s disease. Liver abscess was found to be the underlying trigger for thyrotoxic paralysis and thyroid storm.
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spelling doaj.art-77d0df9839e8474d86f581133e85c2e02022-12-21T20:18:07ZengShahid Beheshti University of Medical SciencesArchives of Academic Emergency Medicine2645-49042021-02-019110.22037/aaem.v9i1.1083Thyrotoxic Periodic Paralysis with Thyroid Storm as the First Presentation of Graves’ disease; a Case ReportTejaswee Banavathu0Swapnil Tripathi1Pankaj Sukhadiya2Kamlesh Ahari3Durga Shankar Meena4Mahendra Kumar Garg5Department of Internal Medicine, All India Institute of Medical Sciences, JodhpurDepartment of Internal Medicine, All India Institute of Medical Sciences, JodhpurDepartment of Internal Medicine, All India Institute of Medical Sciences, JodhpurDepartment of Internal Medicine, All India Institute of Medical Sciences, JodhpurAll India Institute of Medical Sciences, JodhpurDepartment of Internal Medicine, All India Institute of Medical Sciences, JodhpurThyrotoxic periodic paralysis is a rare endocrine emergency that manifests as acute onset muscle weakness and hypokalaemia secondary to thyrotoxicosis. It mainly occurs due to rapid and dramatic intracellular shift of potassium resulting in hypokalaemia and acute flaccid paralysis. This condition predominantly affects males of Asian descent, and presentation can range from mild generalized weakness to complete quadriplegia, as seen in our case. We herein report a case of a 40-year-old female, who presented to us with acute onset flaccid quadriplegia and thyroid storm, which is the first ever manifestation of previously undiagnosed Grave’s disease. Liver abscess was found to be the underlying trigger for thyrotoxic paralysis and thyroid storm.https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/1083Hypokalemic Periodic ParalysisThyrotoxicosisGraves diseaseQuadriplegiaThyroid Crisis
spellingShingle Tejaswee Banavathu
Swapnil Tripathi
Pankaj Sukhadiya
Kamlesh Ahari
Durga Shankar Meena
Mahendra Kumar Garg
Thyrotoxic Periodic Paralysis with Thyroid Storm as the First Presentation of Graves’ disease; a Case Report
Archives of Academic Emergency Medicine
Hypokalemic Periodic Paralysis
Thyrotoxicosis
Graves disease
Quadriplegia
Thyroid Crisis
title Thyrotoxic Periodic Paralysis with Thyroid Storm as the First Presentation of Graves’ disease; a Case Report
title_full Thyrotoxic Periodic Paralysis with Thyroid Storm as the First Presentation of Graves’ disease; a Case Report
title_fullStr Thyrotoxic Periodic Paralysis with Thyroid Storm as the First Presentation of Graves’ disease; a Case Report
title_full_unstemmed Thyrotoxic Periodic Paralysis with Thyroid Storm as the First Presentation of Graves’ disease; a Case Report
title_short Thyrotoxic Periodic Paralysis with Thyroid Storm as the First Presentation of Graves’ disease; a Case Report
title_sort thyrotoxic periodic paralysis with thyroid storm as the first presentation of graves disease a case report
topic Hypokalemic Periodic Paralysis
Thyrotoxicosis
Graves disease
Quadriplegia
Thyroid Crisis
url https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/1083
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