Delivery of Cancer Therapeutics Using Nanotechnology
Nanoparticles have been investigated as drug carriers, because they provide a great opportunity due to their advantageous features: (i) various formulations using organic/inorganic materials, (ii) easy modification of targeting molecules, drugs or other molecules on them, (iii) effective delivery to...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2013-05-01
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| Series: | Pharmaceutics |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1999-4923/5/2/294 |
| _version_ | 1817990692825202688 |
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| author | Kwangyeol Lee Seungjoo Haam Yong-Min Huh Eunji Jang Eun-Kyung Lim |
| author_facet | Kwangyeol Lee Seungjoo Haam Yong-Min Huh Eunji Jang Eun-Kyung Lim |
| author_sort | Kwangyeol Lee |
| collection | DOAJ |
| description | Nanoparticles have been investigated as drug carriers, because they provide a great opportunity due to their advantageous features: (i) various formulations using organic/inorganic materials, (ii) easy modification of targeting molecules, drugs or other molecules on them, (iii) effective delivery to target sites, resulting in high therapeutic efficacy and (iv) controlling drug release by external/internal stimuli. Because of these features, therapeutic efficacy can be improved and unwanted side effects can be reduced. Theranostic nanoparticles have been developed by incorporating imaging agents in drug carriers as all-in-one system, which makes it possible to diagnose and treat cancer by monitoring drug delivery behavior simultaneously. Recently, stimuli-responsive, activatable nanomaterials are being applied that are capable of producing chemical or physical changes by external stimuli. By using these nanoparticles, multiple tasks can be carried out simultaneously, e.g., early and accurate diagnosis, efficient cataloguing of patient groups of personalized therapy and real-time monitoring of disease progress. In this paper, we describe various types of nanoparticles for drug delivery systems, as well as theranostic systems. |
| first_indexed | 2024-04-14T01:02:27Z |
| format | Article |
| id | doaj.art-77d405c8a52c448ea63b85da3793f7ce |
| institution | Directory Open Access Journal |
| issn | 1999-4923 |
| language | English |
| last_indexed | 2024-04-14T01:02:27Z |
| publishDate | 2013-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceutics |
| spelling | doaj.art-77d405c8a52c448ea63b85da3793f7ce2022-12-22T02:21:21ZengMDPI AGPharmaceutics1999-49232013-05-015229431710.3390/pharmaceutics5020294Delivery of Cancer Therapeutics Using NanotechnologyKwangyeol LeeSeungjoo HaamYong-Min HuhEunji JangEun-Kyung LimNanoparticles have been investigated as drug carriers, because they provide a great opportunity due to their advantageous features: (i) various formulations using organic/inorganic materials, (ii) easy modification of targeting molecules, drugs or other molecules on them, (iii) effective delivery to target sites, resulting in high therapeutic efficacy and (iv) controlling drug release by external/internal stimuli. Because of these features, therapeutic efficacy can be improved and unwanted side effects can be reduced. Theranostic nanoparticles have been developed by incorporating imaging agents in drug carriers as all-in-one system, which makes it possible to diagnose and treat cancer by monitoring drug delivery behavior simultaneously. Recently, stimuli-responsive, activatable nanomaterials are being applied that are capable of producing chemical or physical changes by external stimuli. By using these nanoparticles, multiple tasks can be carried out simultaneously, e.g., early and accurate diagnosis, efficient cataloguing of patient groups of personalized therapy and real-time monitoring of disease progress. In this paper, we describe various types of nanoparticles for drug delivery systems, as well as theranostic systems.http://www.mdpi.com/1999-4923/5/2/294nanoparticlesnanotechnologydrug deliverycancertheranostic nanoparticles |
| spellingShingle | Kwangyeol Lee Seungjoo Haam Yong-Min Huh Eunji Jang Eun-Kyung Lim Delivery of Cancer Therapeutics Using Nanotechnology Pharmaceutics nanoparticles nanotechnology drug delivery cancer theranostic nanoparticles |
| title | Delivery of Cancer Therapeutics Using Nanotechnology |
| title_full | Delivery of Cancer Therapeutics Using Nanotechnology |
| title_fullStr | Delivery of Cancer Therapeutics Using Nanotechnology |
| title_full_unstemmed | Delivery of Cancer Therapeutics Using Nanotechnology |
| title_short | Delivery of Cancer Therapeutics Using Nanotechnology |
| title_sort | delivery of cancer therapeutics using nanotechnology |
| topic | nanoparticles nanotechnology drug delivery cancer theranostic nanoparticles |
| url | http://www.mdpi.com/1999-4923/5/2/294 |
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