Human embryonic stem cells derived from abnormal blastocyst donated by Marfan syndrome patient

Human embryonic stem cells derived from abnormal blastocyst donated by Marfan syndrome patient

Human embryonic stem cell (hESC) line was derived from abnormal blastocyst donated by Marfan syndrome patient after preimpantation genetic diagnosis (PGD) treatment. DNA sequencing analysis confirmed that the hESC line carried the heterozygous deletion mutation, c.3536delA, of FBN1 gene. Characteris...

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Bibliographic Details
Main Authors:	Qingqing Yang, Xiaoying Zhou, Hao Zhou, Long Li, Juan Du, Guangxiu Lu, Ge Lin, Qi Ouyang
Format:	Article
Language:	English
Published:	Elsevier 2015-11-01
Series:	Stem Cell Research
Online Access:	http://www.sciencedirect.com/science/article/pii/S1873506115001476

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