Improved function and strength in patients with knee osteoarthritis as a result of adding a two-day educational program to usual care. Prospective randomized trial
Objective: The primary aim was to quantify the improvements on function and pain of patients with knee osteoarthritis (KOA), short education and low income by a two-day self-management program. Secondary aims were verifying if the program improves clinically relevant measures of weight and strength....
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-03-01
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| Series: | Osteoarthritis and Cartilage Open |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2665913120301370 |
| _version_ | 1818694133340962816 |
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| author | MU Rezende NLR Brito FES Farias CAC Silva CHA Cernigoy JM Rodrigues da Silva MM Moreira OFN Santana MI Hissadomi R Frucchi T Pasqualin GC Campos AF Pailo GP Ocampos OP Camargo |
| author_facet | MU Rezende NLR Brito FES Farias CAC Silva CHA Cernigoy JM Rodrigues da Silva MM Moreira OFN Santana MI Hissadomi R Frucchi T Pasqualin GC Campos AF Pailo GP Ocampos OP Camargo |
| author_sort | MU Rezende |
| collection | DOAJ |
| description | Objective: The primary aim was to quantify the improvements on function and pain of patients with knee osteoarthritis (KOA), short education and low income by a two-day self-management program. Secondary aims were verifying if the program improves clinically relevant measures of weight and strength. Design: A prospective randomized clinical trial was conducted in a tertiary hospital in Brazil with 191 patients with Kellgren & Lawrence grades II and III KOA who were allocated to two groups: control (usual care- CG) and intervention (usual care and two days of an OA self-management program with a multiprofessional team - IG). Western Ontario and McMaster Universities Index (WOMAC), weight, body mass index (BMI), Timed up and go (TUG) and five Times Sit to Stand Test (FTSST) were assessed at baseline, six, 12 and 24 months. Results: Groups were similar at baseline (p > 0.05). Both groups exhibited improved WOMAC total and subsets scores throughout the study (p < 0.001). However, only IG improved WOMAC total and subsets in all follow-ups above 20% (minimally clinically important difference), with differences in WOMAC pain, function and total scores (p = 0.001, p < 0.001, and p < 0.001, respectively) and best effect sizes at 1 year (0.355, 0.651 and 0.770, respectively). IG group lost weight (p < 0.001) and BMI (p < 0.01). Both groups exhibited improvements in TUG and FTSST (p < 0.001) that remained in all evaluations. FTSST results favored the IG, p = 0.032. Conclusions: An educational program to patients with KOA, short schooling and low income improves clinically important measures of pain and function. |
| first_indexed | 2024-12-17T13:24:44Z |
| format | Article |
| id | doaj.art-77d9d1f592384d28914f905204fda4a8 |
| institution | Directory Open Access Journal |
| issn | 2665-9131 |
| language | English |
| last_indexed | 2024-12-17T13:24:44Z |
| publishDate | 2021-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Osteoarthritis and Cartilage Open |
| spelling | doaj.art-77d9d1f592384d28914f905204fda4a82022-12-21T21:46:46ZengElsevierOsteoarthritis and Cartilage Open2665-91312021-03-0131100137Improved function and strength in patients with knee osteoarthritis as a result of adding a two-day educational program to usual care. Prospective randomized trialMU Rezende0NLR Brito1FES Farias2CAC Silva3CHA Cernigoy4JM Rodrigues da Silva5MM Moreira6OFN Santana7MI Hissadomi8R Frucchi9T Pasqualin10GC Campos11AF Pailo12GP Ocampos13OP Camargo14Orthopedic and Traumatology Department, Faculty of Medicine of the University of São Paulo (FMUSP), São Paulo, SP, Brazil; Corresponding author.Orthopedic and Traumatology Department, Faculty of Medicine of the University of São Paulo (FMUSP), São Paulo, SP, BrazilOrthopedic and Traumatology Department, Faculty of Medicine of the University of São Paulo (FMUSP), São Paulo, SP, BrazilOrthopedic and Traumatology Department, Faculty of Medicine of the University of São Paulo (FMUSP), São Paulo, SP, BrazilOrthopedic and Traumatology Department, Faculty of Medicine of the University of São Paulo (FMUSP), São Paulo, SP, BrazilSao Paulo State University (UNESP), Bauru, SP, BrazilOrthopedic and Traumatology Department, Faculty of Medicine of the University of São Paulo (FMUSP), São Paulo, SP, BrazilOrthopedic and Traumatology Department, Faculty of Medicine of the University of São Paulo (FMUSP), São Paulo, SP, BrazilOrthopedic and Traumatology Department, Faculty of Medicine of the University of São Paulo (FMUSP), São Paulo, SP, BrazilOrthopedic and Traumatology Department, Faculty of Medicine of the University of São Paulo (FMUSP), São Paulo, SP, BrazilOrthopedic and Traumatology Department, Faculty of Medicine of the University of São Paulo (FMUSP), São Paulo, SP, BrazilState University of Campinas (UNICAMP), Campinas, SP, BrazilOrthopedic and Traumatology Department, Faculty of Medicine of the University of São Paulo (FMUSP), São Paulo, SP, BrazilOrthopedic and Traumatology Department, Faculty of Medicine of the University of São Paulo (FMUSP), São Paulo, SP, BrazilOrthopedic and Traumatology Department, Faculty of Medicine of the University of São Paulo (FMUSP), São Paulo, SP, BrazilObjective: The primary aim was to quantify the improvements on function and pain of patients with knee osteoarthritis (KOA), short education and low income by a two-day self-management program. Secondary aims were verifying if the program improves clinically relevant measures of weight and strength. Design: A prospective randomized clinical trial was conducted in a tertiary hospital in Brazil with 191 patients with Kellgren & Lawrence grades II and III KOA who were allocated to two groups: control (usual care- CG) and intervention (usual care and two days of an OA self-management program with a multiprofessional team - IG). Western Ontario and McMaster Universities Index (WOMAC), weight, body mass index (BMI), Timed up and go (TUG) and five Times Sit to Stand Test (FTSST) were assessed at baseline, six, 12 and 24 months. Results: Groups were similar at baseline (p > 0.05). Both groups exhibited improved WOMAC total and subsets scores throughout the study (p < 0.001). However, only IG improved WOMAC total and subsets in all follow-ups above 20% (minimally clinically important difference), with differences in WOMAC pain, function and total scores (p = 0.001, p < 0.001, and p < 0.001, respectively) and best effect sizes at 1 year (0.355, 0.651 and 0.770, respectively). IG group lost weight (p < 0.001) and BMI (p < 0.01). Both groups exhibited improvements in TUG and FTSST (p < 0.001) that remained in all evaluations. FTSST results favored the IG, p = 0.032. Conclusions: An educational program to patients with KOA, short schooling and low income improves clinically important measures of pain and function.http://www.sciencedirect.com/science/article/pii/S2665913120301370Knee osteoarthritisEducationClinical trialMinimal clinically important differenceDifferential threshold |
| spellingShingle | MU Rezende NLR Brito FES Farias CAC Silva CHA Cernigoy JM Rodrigues da Silva MM Moreira OFN Santana MI Hissadomi R Frucchi T Pasqualin GC Campos AF Pailo GP Ocampos OP Camargo Improved function and strength in patients with knee osteoarthritis as a result of adding a two-day educational program to usual care. Prospective randomized trial Osteoarthritis and Cartilage Open Knee osteoarthritis Education Clinical trial Minimal clinically important difference Differential threshold |
| title | Improved function and strength in patients with knee osteoarthritis as a result of adding a two-day educational program to usual care. Prospective randomized trial |
| title_full | Improved function and strength in patients with knee osteoarthritis as a result of adding a two-day educational program to usual care. Prospective randomized trial |
| title_fullStr | Improved function and strength in patients with knee osteoarthritis as a result of adding a two-day educational program to usual care. Prospective randomized trial |
| title_full_unstemmed | Improved function and strength in patients with knee osteoarthritis as a result of adding a two-day educational program to usual care. Prospective randomized trial |
| title_short | Improved function and strength in patients with knee osteoarthritis as a result of adding a two-day educational program to usual care. Prospective randomized trial |
| title_sort | improved function and strength in patients with knee osteoarthritis as a result of adding a two day educational program to usual care prospective randomized trial |
| topic | Knee osteoarthritis Education Clinical trial Minimal clinically important difference Differential threshold |
| url | http://www.sciencedirect.com/science/article/pii/S2665913120301370 |
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