DIAGNOSTIC PITFALLS OF BRAIN METASTASES AFTER BRAIN IRRADIATION
Although brain metastases are one of the most frequently diagnosed sequelae of systemic malignancy, their optimal management still is not well defined. In that respect the different diagnostic and therapeutic approaches of BMs patients is an issue for serious discussions. Among the most c...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Peytchinski Publishing
2010-11-01
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| Series: | Journal of IMAB |
| Subjects: | |
| Online Access: | http://www.journal-imab-bg.org/statii-10/vol16_b3_p32-37.pdf |
| _version_ | 1818155338778542080 |
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| author | Nikolay A. Peev Svetoslav K. Kalevski Dimiter G. Haritonov |
| author_facet | Nikolay A. Peev Svetoslav K. Kalevski Dimiter G. Haritonov |
| author_sort | Nikolay A. Peev |
| collection | DOAJ |
| description | Although brain metastases are one of the most frequently diagnosed sequelae of systemic malignancy, their optimal management still is not well defined. In that respect the different diagnostic and therapeutic approaches of BMs patients is an issue for serious discussions. Among the most commonly used diagnostic tools are computed tomography (CT) scans, magnetic resonance imaging (MRI) scans, single photon emission computed tomography (SPECT) and positron emission tomography (PET) scans etc. Nowadays the aforementioned diagnostic modalities are usually combined in order to obtain complete diagnostic information important for establishing the optimal treatment. With the present report we try to elaborate on the value of the modern diagnostic tools in differentiating between tumor progressions versus radiation necrosis in irradiated patients with resected brain metastases. Although the present advancement of the modern imaging modalities differentiating between tumor progression versus radiation necrosis is often difficult. Application of the metabolic imaging modalities like SPECT, PET and proton magnetic resonance spectroscopy (1H-MRS) contributes for the diagnose but still pathological specimens remain a gold standard for distinguishing tumor from necrosis, because none of the imaging modalities is possible to reliably differentiate necrosis from progression in 100% of the cases. |
| first_indexed | 2024-12-11T14:40:49Z |
| format | Article |
| id | doaj.art-77da778a8a1e45a3bbf5230c31ae6d38 |
| institution | Directory Open Access Journal |
| issn | 1312-773X |
| language | English |
| last_indexed | 2024-12-11T14:40:49Z |
| publishDate | 2010-11-01 |
| publisher | Peytchinski Publishing |
| record_format | Article |
| series | Journal of IMAB |
| spelling | doaj.art-77da778a8a1e45a3bbf5230c31ae6d382022-12-22T01:01:56ZengPeytchinski PublishingJournal of IMAB1312-773X2010-11-01163323710.5272/jimab.1632010_32-37DIAGNOSTIC PITFALLS OF BRAIN METASTASES AFTER BRAIN IRRADIATIONNikolay A. PeevSvetoslav K. KalevskiDimiter G. HaritonovAlthough brain metastases are one of the most frequently diagnosed sequelae of systemic malignancy, their optimal management still is not well defined. In that respect the different diagnostic and therapeutic approaches of BMs patients is an issue for serious discussions. Among the most commonly used diagnostic tools are computed tomography (CT) scans, magnetic resonance imaging (MRI) scans, single photon emission computed tomography (SPECT) and positron emission tomography (PET) scans etc. Nowadays the aforementioned diagnostic modalities are usually combined in order to obtain complete diagnostic information important for establishing the optimal treatment. With the present report we try to elaborate on the value of the modern diagnostic tools in differentiating between tumor progressions versus radiation necrosis in irradiated patients with resected brain metastases. Although the present advancement of the modern imaging modalities differentiating between tumor progression versus radiation necrosis is often difficult. Application of the metabolic imaging modalities like SPECT, PET and proton magnetic resonance spectroscopy (1H-MRS) contributes for the diagnose but still pathological specimens remain a gold standard for distinguishing tumor from necrosis, because none of the imaging modalities is possible to reliably differentiate necrosis from progression in 100% of the cases.http://www.journal-imab-bg.org/statii-10/vol16_b3_p32-37.pdfbrain metastasesgamma knifesurgical resectionstereo tactic radio surgerymetabolic imaging modalities |
| spellingShingle | Nikolay A. Peev Svetoslav K. Kalevski Dimiter G. Haritonov DIAGNOSTIC PITFALLS OF BRAIN METASTASES AFTER BRAIN IRRADIATION Journal of IMAB brain metastases gamma knife surgical resection stereo tactic radio surgery metabolic imaging modalities |
| title | DIAGNOSTIC PITFALLS OF BRAIN METASTASES AFTER BRAIN IRRADIATION |
| title_full | DIAGNOSTIC PITFALLS OF BRAIN METASTASES AFTER BRAIN IRRADIATION |
| title_fullStr | DIAGNOSTIC PITFALLS OF BRAIN METASTASES AFTER BRAIN IRRADIATION |
| title_full_unstemmed | DIAGNOSTIC PITFALLS OF BRAIN METASTASES AFTER BRAIN IRRADIATION |
| title_short | DIAGNOSTIC PITFALLS OF BRAIN METASTASES AFTER BRAIN IRRADIATION |
| title_sort | diagnostic pitfalls of brain metastases after brain irradiation |
| topic | brain metastases gamma knife surgical resection stereo tactic radio surgery metabolic imaging modalities |
| url | http://www.journal-imab-bg.org/statii-10/vol16_b3_p32-37.pdf |
| work_keys_str_mv | AT nikolayapeev diagnosticpitfallsofbrainmetastasesafterbrainirradiation AT svetoslavkkalevski diagnosticpitfallsofbrainmetastasesafterbrainirradiation AT dimitergharitonov diagnosticpitfallsofbrainmetastasesafterbrainirradiation |