Setting up child health and mortality prevention surveillance in Ethiopia [version 2; peer review: 2 approved, 1 approved with reservations]
Background: Mortality rates for children under five years of age, and stillbirth risks, remain high in parts of sub-Saharan Africa and South Asia. The Child Health and Mortality Prevention Surveillance (CHAMPS) network aims to ascertain causes of child death in high child mortality settings (>50...
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| Format: | Artikel |
| Sprache: | English |
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F1000 Research Ltd
2022-02-01
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| Schriftenreihe: | Gates Open Research |
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| Online Zugang: | https://gatesopenresearch.org/articles/5-173/v2 |
| _version_ | 1828152306896470016 |
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| author | Anna C. Seale Lola Madrid Nega Assefa Hanan Abdurahman Stefanie Wittmann Letta Gedefa Nardos Teferi Natnael Debela Alexander Mohamed Tigistu Samuel Tseyon Tesfaye Hiwot Yigzaw Mehret Dubale Workalemahu Bekele Eyoel Taye Gutema Imana Keno Caroline Ackley Zerihun Girma Yosef Zegeye Berhanu Damisse Ketema Degefa Mohammed Aliyi Adugna Tadesse Yenenesh Tilahun Gurmu Feyissa Bizunesh Sintayehu Getahun Wakwaya Addisu Alemu Getamesay Abayneh Joe Oundo Emmanuel Azore Dadi Marami Zelalem T Mariam Mussie Berhanu Mulu Berihun Andualem Alemayehu Mahlet Mekonnen Shirine Voller Nana Sarkodie-Mensah Abraham Aseffa Boniface Jibendi Robert F. Breiman Taye Balcha Asnake Worku Scott F Dowell Ebba Abate Tsigereda Kifle J. Anthony G. Scott Yadeta Dessie |
| author_facet | Anna C. Seale Lola Madrid Nega Assefa Hanan Abdurahman Stefanie Wittmann Letta Gedefa Nardos Teferi Natnael Debela Alexander Mohamed Tigistu Samuel Tseyon Tesfaye Hiwot Yigzaw Mehret Dubale Workalemahu Bekele Eyoel Taye Gutema Imana Keno Caroline Ackley Zerihun Girma Yosef Zegeye Berhanu Damisse Ketema Degefa Mohammed Aliyi Adugna Tadesse Yenenesh Tilahun Gurmu Feyissa Bizunesh Sintayehu Getahun Wakwaya Addisu Alemu Getamesay Abayneh Joe Oundo Emmanuel Azore Dadi Marami Zelalem T Mariam Mussie Berhanu Mulu Berihun Andualem Alemayehu Mahlet Mekonnen Shirine Voller Nana Sarkodie-Mensah Abraham Aseffa Boniface Jibendi Robert F. Breiman Taye Balcha Asnake Worku Scott F Dowell Ebba Abate Tsigereda Kifle J. Anthony G. Scott Yadeta Dessie |
| author_sort | Anna C. Seale |
| collection | DOAJ |
| description | Background: Mortality rates for children under five years of age, and stillbirth risks, remain high in parts of sub-Saharan Africa and South Asia. The Child Health and Mortality Prevention Surveillance (CHAMPS) network aims to ascertain causes of child death in high child mortality settings (>50 deaths/1000 live-births). We aimed to develop a “greenfield” site for CHAMPS, based in Harar and Kersa, in Eastern Ethiopia. This very high mortality setting (>100 deaths/1000 live-births in Kersa) had limited previous surveillance capacity, weak infrastructure and political instability. Here we describe site development, from conception in 2015 to the end of the first year of recruitment. Methods: We formed a collaboration between Haramaya University and the London School of Hygiene & Tropical Medicine and engaged community, national and international partners to support a new CHAMPS programme. We developed laboratory infrastructure and recruited and trained staff. We established project specific procedures to implement CHAMPS network protocols including; death notifications, clinical and demographic data collection, post-mortem minimally invasive tissue sampling, microbiology and pathology testing, and verbal autopsy. We convened an expert local panel to determine cause-of-death. In partnership with the Ethiopian Public Health Institute we developed strategies to improve child and maternal health. Results: Despite considerable challenge, with financial support, personal commitment, and effective partnership, we successfully initiated CHAMPS. One year into recruitment (February 2020), we had received 1173 unique death notifications, investigated 59/99 MITS-eligible cases within the demographic surveillance site, and assigned an underlying and immediate cause of death to 53 children. Conclusions: The most valuable data for global health policy are from high-mortality settings, but initiating CHAMPS has required considerable resource. To further leverage this investment, we need strong, sustained, local research leadership, and to broaden the scientific remit. To support this, we have set up a new collaboration, the “Hararghe Health Research Partnership”. |
| first_indexed | 2024-04-11T22:10:07Z |
| format | Article |
| id | doaj.art-77daa26b51e44e69b4fed84a29937c62 |
| institution | Directory Open Access Journal |
| issn | 2572-4754 |
| language | English |
| last_indexed | 2024-04-11T22:10:07Z |
| publishDate | 2022-02-01 |
| publisher | F1000 Research Ltd |
| record_format | Article |
| series | Gates Open Research |
| spelling | doaj.art-77daa26b51e44e69b4fed84a29937c622022-12-22T04:00:36ZengF1000 Research LtdGates Open Research2572-47542022-02-01514836Setting up child health and mortality prevention surveillance in Ethiopia [version 2; peer review: 2 approved, 1 approved with reservations]Anna C. Seale0Lola Madrid1https://orcid.org/0000-0003-4034-6033Nega Assefa2https://orcid.org/0000-0003-0341-2329Hanan Abdurahman3Stefanie Wittmann4Letta Gedefa5Nardos Teferi6Natnael Debela7Alexander Mohamed8Tigistu Samuel9Tseyon Tesfaye10Hiwot Yigzaw11Mehret Dubale12Workalemahu Bekele13Eyoel Taye14https://orcid.org/0000-0003-0526-450XGutema Imana Keno15Caroline Ackley16Zerihun Girma17Yosef Zegeye18Berhanu Damisse19https://orcid.org/0000-0002-1696-3747Ketema Degefa20Mohammed Aliyi21Adugna Tadesse22https://orcid.org/0000-0003-1990-2576Yenenesh Tilahun23Gurmu Feyissa24Bizunesh Sintayehu25Getahun Wakwaya26Addisu Alemu27https://orcid.org/0000-0002-8219-6259Getamesay Abayneh28Joe Oundo29Emmanuel Azore30Dadi Marami31https://orcid.org/0000-0002-4793-3575Zelalem T Mariam32Mussie Berhanu33https://orcid.org/0000-0001-9552-2351Mulu Berihun34Andualem Alemayehu35Mahlet Mekonnen36Shirine Voller37https://orcid.org/0000-0001-7382-8675Nana Sarkodie-Mensah38Abraham Aseffa39https://orcid.org/0000-0002-8028-1150Boniface Jibendi40Robert F. Breiman41https://orcid.org/0000-0002-7099-2936Taye Balcha42Asnake Worku43Scott F Dowell44https://orcid.org/0000-0002-3878-5056Ebba Abate45Tsigereda Kifle46J. Anthony G. Scott47Yadeta Dessie48Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UKEpidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UKEpidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UKHaramaya University, Oromia, EthiopiaEpidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UKHaramaya University, Oromia, EthiopiaHaramaya University, Oromia, EthiopiaHaramaya University, Oromia, EthiopiaHaramaya University, Oromia, EthiopiaHaramaya University, Oromia, EthiopiaHaramaya University, Oromia, EthiopiaHaramaya University, Oromia, EthiopiaEpidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UKHaramaya University, Oromia, EthiopiaHaramaya University, Oromia, EthiopiaHaramaya University, Oromia, EthiopiaEpidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UKHaramaya University, Oromia, EthiopiaHaramaya University, Oromia, EthiopiaHaramaya University, Oromia, EthiopiaHaramaya University, Oromia, EthiopiaHaramaya University, Oromia, EthiopiaHaramaya University, Oromia, EthiopiaHaramaya University, Oromia, EthiopiaHaramaya University, Oromia, EthiopiaHaramaya University, Oromia, EthiopiaHaramaya University, Oromia, EthiopiaHaramaya University, Oromia, EthiopiaHaramaya University, Oromia, EthiopiaEpidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UKEpidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UKHaramaya University, Oromia, EthiopiaHaramaya University, Oromia, EthiopiaHaramaya University, Oromia, EthiopiaHaramaya University, Oromia, EthiopiaHaramaya University, Oromia, EthiopiaHaramaya University, Oromia, EthiopiaEpidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UKEpidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UKArmauer Hansen Research Institute, Addis Ababa, EthiopiaEpidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UKEmory Global Health Institute, Emory University, USAArmauer Hansen Research Institute, Addis Ababa, EthiopiaEthiopian Public Health Institute, Addis Ababa, EthiopiaBill & Melinda Gates Foundation, Seattle, USAEthiopian Public Health Institute, Addis Ababa, EthiopiaEthiopian Public Health Institute, Addis Ababa, EthiopiaEpidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UKHaramaya University, Oromia, EthiopiaBackground: Mortality rates for children under five years of age, and stillbirth risks, remain high in parts of sub-Saharan Africa and South Asia. The Child Health and Mortality Prevention Surveillance (CHAMPS) network aims to ascertain causes of child death in high child mortality settings (>50 deaths/1000 live-births). We aimed to develop a “greenfield” site for CHAMPS, based in Harar and Kersa, in Eastern Ethiopia. This very high mortality setting (>100 deaths/1000 live-births in Kersa) had limited previous surveillance capacity, weak infrastructure and political instability. Here we describe site development, from conception in 2015 to the end of the first year of recruitment. Methods: We formed a collaboration between Haramaya University and the London School of Hygiene & Tropical Medicine and engaged community, national and international partners to support a new CHAMPS programme. We developed laboratory infrastructure and recruited and trained staff. We established project specific procedures to implement CHAMPS network protocols including; death notifications, clinical and demographic data collection, post-mortem minimally invasive tissue sampling, microbiology and pathology testing, and verbal autopsy. We convened an expert local panel to determine cause-of-death. In partnership with the Ethiopian Public Health Institute we developed strategies to improve child and maternal health. Results: Despite considerable challenge, with financial support, personal commitment, and effective partnership, we successfully initiated CHAMPS. One year into recruitment (February 2020), we had received 1173 unique death notifications, investigated 59/99 MITS-eligible cases within the demographic surveillance site, and assigned an underlying and immediate cause of death to 53 children. Conclusions: The most valuable data for global health policy are from high-mortality settings, but initiating CHAMPS has required considerable resource. To further leverage this investment, we need strong, sustained, local research leadership, and to broaden the scientific remit. To support this, we have set up a new collaboration, the “Hararghe Health Research Partnership”.https://gatesopenresearch.org/articles/5-173/v2surveillance Ethiopia mortality deaths child infanteng |
| spellingShingle | Anna C. Seale Lola Madrid Nega Assefa Hanan Abdurahman Stefanie Wittmann Letta Gedefa Nardos Teferi Natnael Debela Alexander Mohamed Tigistu Samuel Tseyon Tesfaye Hiwot Yigzaw Mehret Dubale Workalemahu Bekele Eyoel Taye Gutema Imana Keno Caroline Ackley Zerihun Girma Yosef Zegeye Berhanu Damisse Ketema Degefa Mohammed Aliyi Adugna Tadesse Yenenesh Tilahun Gurmu Feyissa Bizunesh Sintayehu Getahun Wakwaya Addisu Alemu Getamesay Abayneh Joe Oundo Emmanuel Azore Dadi Marami Zelalem T Mariam Mussie Berhanu Mulu Berihun Andualem Alemayehu Mahlet Mekonnen Shirine Voller Nana Sarkodie-Mensah Abraham Aseffa Boniface Jibendi Robert F. Breiman Taye Balcha Asnake Worku Scott F Dowell Ebba Abate Tsigereda Kifle J. Anthony G. Scott Yadeta Dessie Setting up child health and mortality prevention surveillance in Ethiopia [version 2; peer review: 2 approved, 1 approved with reservations] Gates Open Research surveillance Ethiopia mortality deaths child infant eng |
| title | Setting up child health and mortality prevention surveillance in Ethiopia [version 2; peer review: 2 approved, 1 approved with reservations] |
| title_full | Setting up child health and mortality prevention surveillance in Ethiopia [version 2; peer review: 2 approved, 1 approved with reservations] |
| title_fullStr | Setting up child health and mortality prevention surveillance in Ethiopia [version 2; peer review: 2 approved, 1 approved with reservations] |
| title_full_unstemmed | Setting up child health and mortality prevention surveillance in Ethiopia [version 2; peer review: 2 approved, 1 approved with reservations] |
| title_short | Setting up child health and mortality prevention surveillance in Ethiopia [version 2; peer review: 2 approved, 1 approved with reservations] |
| title_sort | setting up child health and mortality prevention surveillance in ethiopia version 2 peer review 2 approved 1 approved with reservations |
| topic | surveillance Ethiopia mortality deaths child infant eng |
| url | https://gatesopenresearch.org/articles/5-173/v2 |
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