The clinical neurophysiology of COVID-19-direct infection, long-term sequelae and para-immunization responses: A literature review

The COVID-19 pandemic resulting from the SARS-CoV-2 virus is in its third year. There is continuously evolving information regarding its pathophysiology and its effects on the nervous system. Clinical neurophysiology techniques are commonly employed to assess for neuroanatomical localization and/or...

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Main Authors: M. Ayman Haykal, Daniel L. Menkes
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Clinical Neurophysiology Practice
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2467981X22000397
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author M. Ayman Haykal
Daniel L. Menkes
author_facet M. Ayman Haykal
Daniel L. Menkes
author_sort M. Ayman Haykal
collection DOAJ
description The COVID-19 pandemic resulting from the SARS-CoV-2 virus is in its third year. There is continuously evolving information regarding its pathophysiology and its effects on the nervous system. Clinical neurophysiology techniques are commonly employed to assess for neuroanatomical localization and/or defining the spectrum of neurological illness. There is an evolving body of literature delineating the effects of the SARS-CoV-2 virus on the nervous system as well as para-immunization responses to vaccination against this virus. This review focuses on the use of neurophysiological diagnostic modalities in the evaluation of potential acute and long-term neurological complications in patients that experience direct infection with SARS-CoV-2 and analyzes those reports of para-immunization responses to vaccination against the SARS-CoV-2 virus. The neurophysiological modalities to be discussed include electroencephalography (EEG), evoked potentials (EPs), nerve conduction studies and electromyography (EMG/NCV), autonomic function tests, transcranial magnetic stimulation (TMS) and Transcranial Doppler ultrasound (TCD).
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spelling doaj.art-77dbda2a78da44858a37ea0a0736632f2023-12-18T04:24:29ZengElsevierClinical Neurophysiology Practice2467-981X2023-01-018311The clinical neurophysiology of COVID-19-direct infection, long-term sequelae and para-immunization responses: A literature reviewM. Ayman Haykal0Daniel L. Menkes1Corresponding author.; Neurology Department, Oakland University William Beaumont School of Medicine, 3555 West 13 Mile Road, Suite 120, Royal Oak, MI 48073, USANeurology Department, Oakland University William Beaumont School of Medicine, 3555 West 13 Mile Road, Suite 120, Royal Oak, MI 48073, USAThe COVID-19 pandemic resulting from the SARS-CoV-2 virus is in its third year. There is continuously evolving information regarding its pathophysiology and its effects on the nervous system. Clinical neurophysiology techniques are commonly employed to assess for neuroanatomical localization and/or defining the spectrum of neurological illness. There is an evolving body of literature delineating the effects of the SARS-CoV-2 virus on the nervous system as well as para-immunization responses to vaccination against this virus. This review focuses on the use of neurophysiological diagnostic modalities in the evaluation of potential acute and long-term neurological complications in patients that experience direct infection with SARS-CoV-2 and analyzes those reports of para-immunization responses to vaccination against the SARS-CoV-2 virus. The neurophysiological modalities to be discussed include electroencephalography (EEG), evoked potentials (EPs), nerve conduction studies and electromyography (EMG/NCV), autonomic function tests, transcranial magnetic stimulation (TMS) and Transcranial Doppler ultrasound (TCD).http://www.sciencedirect.com/science/article/pii/S2467981X22000397COVID-19NeurophysiologyEEGEMGNCVEvoked potentials
spellingShingle M. Ayman Haykal
Daniel L. Menkes
The clinical neurophysiology of COVID-19-direct infection, long-term sequelae and para-immunization responses: A literature review
Clinical Neurophysiology Practice
COVID-19
Neurophysiology
EEG
EMG
NCV
Evoked potentials
title The clinical neurophysiology of COVID-19-direct infection, long-term sequelae and para-immunization responses: A literature review
title_full The clinical neurophysiology of COVID-19-direct infection, long-term sequelae and para-immunization responses: A literature review
title_fullStr The clinical neurophysiology of COVID-19-direct infection, long-term sequelae and para-immunization responses: A literature review
title_full_unstemmed The clinical neurophysiology of COVID-19-direct infection, long-term sequelae and para-immunization responses: A literature review
title_short The clinical neurophysiology of COVID-19-direct infection, long-term sequelae and para-immunization responses: A literature review
title_sort clinical neurophysiology of covid 19 direct infection long term sequelae and para immunization responses a literature review
topic COVID-19
Neurophysiology
EEG
EMG
NCV
Evoked potentials
url http://www.sciencedirect.com/science/article/pii/S2467981X22000397
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