Signatures of memory: brain coactivations during retrieval distinguish correct from incorrect recollection
Are specific distributed coactivations in the brain during memory retrieval a signature of retrieval outcome? Here we show that this is indeed the case. Widespread brain networks were reported to be involved in the retrieval of long-term episodic memories. Although functional coactivation among part...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2010-04-01
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| Series: | Frontiers in Behavioral Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnbeh.2010.00018/full |
| _version_ | 1818194644477935616 |
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| author | Avi Mendelsohn Orit Furman Yadin Dudai |
| author_facet | Avi Mendelsohn Orit Furman Yadin Dudai |
| author_sort | Avi Mendelsohn |
| collection | DOAJ |
| description | Are specific distributed coactivations in the brain during memory retrieval a signature of retrieval outcome? Here we show that this is indeed the case. Widespread brain networks were reported to be involved in the retrieval of long-term episodic memories. Although functional coactivation among particular regions occurs during episodic memory retrieval, it is unknown to what extent it contributes to the accuracy and confidence of recollection. In this study we set out to explore this question. Participants saw a narrative documentary movie. A week later they underwent an fMRI scan during which they either accepted or rejected factual or fictitious verbal statements concerning the movie. Correct vs. incorrect responses to factual statements were more common and were provided with higher confidence than those made to fictitious statements. Whereas activity in the retrieval network correlated mostly with confidence, coactivations primarily correlated with memory accuracy. Specifically, coactivations of left medial temporal lobe regions with temporal and parietal cortices were greater during correct responses to factual statements, but did not differ between responses to fictitious statements. We propose that network coactivations play a role in recovering memory traces that are relevant to online retrieval cues, culminating in distinct retrieval outcomes. |
| first_indexed | 2024-12-12T01:05:34Z |
| format | Article |
| id | doaj.art-77de7e4e2a7f4b6ca4b7a53c6cf53205 |
| institution | Directory Open Access Journal |
| issn | 1662-5153 |
| language | English |
| last_indexed | 2024-12-12T01:05:34Z |
| publishDate | 2010-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Behavioral Neuroscience |
| spelling | doaj.art-77de7e4e2a7f4b6ca4b7a53c6cf532052022-12-22T00:43:36ZengFrontiers Media S.A.Frontiers in Behavioral Neuroscience1662-51532010-04-01410.3389/fnbeh.2010.000181386Signatures of memory: brain coactivations during retrieval distinguish correct from incorrect recollectionAvi Mendelsohn0Orit Furman1Yadin Dudai2Weizmann Institute of ScienceWeizmann Institute of ScienceWeizmann Institute of ScienceAre specific distributed coactivations in the brain during memory retrieval a signature of retrieval outcome? Here we show that this is indeed the case. Widespread brain networks were reported to be involved in the retrieval of long-term episodic memories. Although functional coactivation among particular regions occurs during episodic memory retrieval, it is unknown to what extent it contributes to the accuracy and confidence of recollection. In this study we set out to explore this question. Participants saw a narrative documentary movie. A week later they underwent an fMRI scan during which they either accepted or rejected factual or fictitious verbal statements concerning the movie. Correct vs. incorrect responses to factual statements were more common and were provided with higher confidence than those made to fictitious statements. Whereas activity in the retrieval network correlated mostly with confidence, coactivations primarily correlated with memory accuracy. Specifically, coactivations of left medial temporal lobe regions with temporal and parietal cortices were greater during correct responses to factual statements, but did not differ between responses to fictitious statements. We propose that network coactivations play a role in recovering memory traces that are relevant to online retrieval cues, culminating in distinct retrieval outcomes.http://journal.frontiersin.org/Journal/10.3389/fnbeh.2010.00018/fullfMRIepisodic memoryLong-term memoryretrievalfunctional coactivationmedial temporal lobe |
| spellingShingle | Avi Mendelsohn Orit Furman Yadin Dudai Signatures of memory: brain coactivations during retrieval distinguish correct from incorrect recollection Frontiers in Behavioral Neuroscience fMRI episodic memory Long-term memory retrieval functional coactivation medial temporal lobe |
| title | Signatures of memory: brain coactivations during retrieval distinguish correct from incorrect recollection |
| title_full | Signatures of memory: brain coactivations during retrieval distinguish correct from incorrect recollection |
| title_fullStr | Signatures of memory: brain coactivations during retrieval distinguish correct from incorrect recollection |
| title_full_unstemmed | Signatures of memory: brain coactivations during retrieval distinguish correct from incorrect recollection |
| title_short | Signatures of memory: brain coactivations during retrieval distinguish correct from incorrect recollection |
| title_sort | signatures of memory brain coactivations during retrieval distinguish correct from incorrect recollection |
| topic | fMRI episodic memory Long-term memory retrieval functional coactivation medial temporal lobe |
| url | http://journal.frontiersin.org/Journal/10.3389/fnbeh.2010.00018/full |
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