Linking Microdosimetric Measurements to Biological Effectiveness in Ion Beam Therapy: A Review of Theoretical Aspects of MKM and Other Models

Linking Microdosimetric Measurements to Biological Effectiveness in Ion Beam Therapy: A Review of Theoretical Aspects of MKM and Other Models

Different qualities of radiation are known to cause different biological effects at the same absorbed dose. Enhancements of the biological effectiveness are a direct consequence of the energy deposition clustering at the scales of DNA molecule and cell nucleus whilst absorbed dose is a macroscopic a...

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Bibliographic Details
Main Authors:	V. E. Bellinzona, F. Cordoni, M. Missiaggia, F. Tommasino, E. Scifoni, C. La Tessa, A. Attili
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-02-01
Series:	Frontiers in Physics
Subjects:	microdosimetry microdosimetric kinetic model relative biological effectiveness oxygen enhancement ratio biophysical modeling ion beam therapy
Online Access:	https://www.frontiersin.org/articles/10.3389/fphy.2020.578492/full

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