Gut microbiome depletion and repetitive mild traumatic brain injury differentially modify bone development in male and female adolescent rats

Gut microbiome depletion and repetitive mild traumatic brain injury differentially modify bone development in male and female adolescent rats

Dysregulation of the gut microbiome has been shown to disrupt both bone formation and bone resorption in several preclinical and clinical models. However, the role of microbiome in adolescent bone development remains poorly understood. This effect of disrupted bone development may be more pronounced...

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Bibliographic Details
Main Authors: Ker Rui Wong, Marissa Sgro, Glenn R. Yamakawa, Crystal Li, Stuart J. McDonald, Mujun Sun, Sandy R. Shultz, Rhys D. Brady, Richelle Mychasiuk
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Bone Reports
Subjects:
Antibiotics
Concussion
Femur
Musculoskeletal
Sex differences
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187221003806

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