SPOR Proteins Are Required for Functionality of Class A Penicillin-Binding Proteins in <named-content content-type="genus-species">Escherichia coli</named-content>

ABSTRACT Sporulation-related repeat (SPOR) domains are present in many bacterial cell envelope proteins and are known to bind peptidoglycan. Escherichia coli contains four SPOR proteins, DamX, DedD, FtsN, and RlpA, of which FtsN is essential for septal peptidoglycan synthesis. DamX and DedD may also...

Full description

Bibliographic Details
Main Authors: Manuel Pazos, Katharina Peters, Adrien Boes, Yalda Safaei, Calem Kenward, Nathanael A. Caveney, Cedric Laguri, Eefjan Breukink, Natalie C. J. Strynadka, Jean-Pierre Simorre, Mohammed Terrak, Waldemar Vollmer
Format: Article
Language:English
Published: American Society for Microbiology 2020-12-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.02796-20