Distribution, Function, and Expression of the Apelinergic System in the Healthy and Diseased Mammalian Brain

Distribution, Function, and Expression of the Apelinergic System in the Healthy and Diseased Mammalian Brain

Apelin, a peptide initially isolated from bovine stomach extract, is an endogenous ligand for the Apelin Receptor (APLNR). Subsequently, a second peptide, ELABELA, that can bind to the receptor has been identified. The Apelin receptor and its endogenous ligands are widely distributed in mammalian or...

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Bibliographic Details
Main Authors: Martin N. Ivanov, Dimo S. Stoyanov, Stoyan P. Pavlov, Anton. B. Tonchev
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Genes
Subjects:
APLNR
APJ
Apelin
ELABELA
CNS
CNS-associated diseases
Online Access:https://www.mdpi.com/2073-4425/13/11/2172

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