Development of a CLDN18.2-targeting immuno-PET probe for non-invasive imaging in gastrointestinal tumors

Development of a CLDN18.2-targeting immuno-PET probe for non-invasive imaging in gastrointestinal tumors

Claudin18.2 (CLDN18.2) is a tight junction protein that is overexpressed in a variety of solid tumors such as gastrointestinal cancer and oesophageal cancer. It has been identified as a promising target and a potential biomarker to diagnose tumor, evaluate efficacy, and determine patient prognosis....

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Bibliographic Details
Main Authors: Yan Chen, Xingguo Hou, Dapeng Li, Jin Ding, Jiayue Liu, Zilei Wang, Fei Teng, Hongjun Li, Fan Zhang, Yi Gu, Steven Yu, Xueming Qian, Zhi Yang, Hua Zhu
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Journal of Pharmaceutical Analysis
Subjects:
Claudin18.2
Gastrointestinal cancers
Zirconium-89
Positron emission tomography
Good Manufacturing Practices
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177923000357

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http://www.sciencedirect.com/science/article/pii/S2095177923000357

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