Unusual presentation of sarcoidosis: solitary intracranial mass lesion mimicking an intracranial neoplasm: a case report

Sarcoidosis is a multisystem disease of unknown cause and with a worldwide distribution. Involvement of the central nervous system occurs in a relatively small number of patients with sarcoidosis. Isolated neurosarcoidosis without signs of systemic disease however is a rare. In this report, we prese...

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Bibliographic Details
Main Authors: Amen Ghozzi, Heifa Azouz, Ines Chelly, Haifa Nfoussi, Hafedh Jemal, Nidhameddine Kchir, Slim Haouet, Moncef Zitouna
Format: Article
Language:English
Published: The Pan African Medical Journal 2014-07-01
Series:The Pan African Medical Journal
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Online Access: https://www.panafrican-med-journal.com/content/article/18/236/pdf/236.pdf
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Summary:Sarcoidosis is a multisystem disease of unknown cause and with a worldwide distribution. Involvement of the central nervous system occurs in a relatively small number of patients with sarcoidosis. Isolated neurosarcoidosis without signs of systemic disease however is a rare. In this report, we present an unusual case of neurosarcoidosis with intra cranial mass mimicking radiologically a glioma. Pathological examination revealed intraparenchymatous necrotising granulomatous lesions. After clinicopathological correlation, the diagnosis of a necrotizing cerebral granulomatosis (neurosarcoidosis) with atypical systemic involvement was made. Because of its non-specific clinical presentation and neuroradiological imaging characteristics, intracranial neurosarcoidosis remains a very difficult diagnosis, particularly in the absence of systemic signs of the disease.
ISSN:1937-8688
1937-8688