FAM134B induces tumorigenesis and epithelial‐to‐mesenchymal transition via Akt signaling in hepatocellular carcinoma

FAM134B induces tumorigenesis and epithelial‐to‐mesenchymal transition via Akt signaling in hepatocellular carcinoma

Fam134b (JK‐1, RETREG1) was first identified as an oncogene in esophageal squamous cell carcinoma. However, the roles of FAM134B during tumorigenesis of hepatocellular carcinoma (HCC) and in epithelial‐to‐mesenchymal transition (EMT) were previously unclear. In this study, we investigated the functi...

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Bibliographic Details
Main Authors: Zhao‐qi Zhang, Jin Chen, Wan‐qiu Huang, Deng Ning, Qiu‐meng Liu, Chao Wang, Long Zhang, Li Ren, Liang Chu, Hui‐fang Liang, Hai‐ning Fan, Bi‐xiang Zhang, Xiao‐ping Chen
Format: Article
Language:English
Published: Wiley 2019-04-01
Series:Molecular Oncology
Subjects:
Akt
epithelial‐to‐mesenchymal transition
FAM134B
HCC
RETREG1
Online Access:https://doi.org/10.1002/1878-0261.12429

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