The changing landscape of automated insulin delivery in the management of type 1 diabetes
Automated insulin delivery systems, also known as closed-loop o r ‘artificial pancreas’ systems, are transforming the management of type 1 diabetes. These systems consist of an algorithm which responds to real-time glucose sensor levels by automatically modulating insulin delivery through an insulin...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Bioscientifica
2023-08-01
|
| Series: | Endocrine Connections |
| Subjects: | |
| Online Access: | https://ec.bioscientifica.com/view/journals/ec/12/8/EC-23-0132.xml |
| Summary: | Automated insulin delivery systems, also known as closed-loop o r ‘artificial pancreas’ systems, are transforming the management of type 1 diabetes. These systems consist of an algorithm which responds to real-time glucose sensor levels by automatically modulating insulin delivery through an insulin pump. We review the rapidly changing landscape of automated insulin-delivery systems over recent decades, from initial prototypes to the different hybrid closed-loop systems commercially available today. We discuss the growing body of clinical trials and real-world evidence demonst rating their glycaemic and psychosocial benefits. We also address future directions in auto mated insulin delivery such as dual-hormone systems and adjunct therapy as well as the chal lenges around ensuring equitable access to closed-loop technology. |
|---|---|
| ISSN: | 2049-3614 |