Coptisine Attenuates Diabetes—Associated Endothelial Dysfunction through Inhibition of Endoplasmic Reticulum Stress and Oxidative Stress

Coptisine Attenuates Diabetes—Associated Endothelial Dysfunction through Inhibition of Endoplasmic Reticulum Stress and Oxidative Stress

Coptisine is the major bioactive protoberberine alkaloid found in <i>Rhizoma Coptidis.</i> Coptisine reduces inflammatory responses and improves glucose tolerance; nevertheless, whether coptisine has vasoprotective effect in diabetes is not fully characterized. Conduit arteries including...

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Bibliographic Details
Main Authors: Yan Zhou, Chunxiu Zhou, Xutao Zhang, Chi Teng Vong, Yitao Wang, Wai San Cheang
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Molecules
Subjects:
coptisine
diabetes
endoplasmic reticulum stress
endothelial dysfunction
oxidative stress
Online Access:https://www.mdpi.com/1420-3049/26/14/4210

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