Coronavirus disease 2019 gastrointestinal and liver manifestations in adults: A review
Abstract Coronavirus disease 2019 (COVID‐19) is an important health problem that has a serious adverse impact on the global economy and healthcare systems. The virus is not only involved in the respiratory system, but also causes other systemic effects as well as several gastrointestinal and liver i...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-11-01
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| Series: | JGH Open |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/jgh3.12671 |
| _version_ | 1818743433826664448 |
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| author | Apichet Sirinawasatien Tanyaporn Chantarojanasiri Sirina Ekpanyapong Naris Tivatunsakul Viravarn Luvira |
| author_facet | Apichet Sirinawasatien Tanyaporn Chantarojanasiri Sirina Ekpanyapong Naris Tivatunsakul Viravarn Luvira |
| author_sort | Apichet Sirinawasatien |
| collection | DOAJ |
| description | Abstract Coronavirus disease 2019 (COVID‐19) is an important health problem that has a serious adverse impact on the global economy and healthcare systems. The virus is not only involved in the respiratory system, but also causes other systemic effects as well as several gastrointestinal and liver issues. Evidence has shown direct viral invasion into the gastrointestinal tissue and supporting vascular network, causing various manifestations such as diarrhea, nausea, gastrointestinal bleeding, and abnormal liver function tests. The degree of gastrointestinal injury, especially in terms of liver involvement, is correlated with disease severity. There is no specific treatment for gastrointestinal involvement, and the symptoms can be managed with supportive therapy. Moreover, increased liver decompensation and mortality can be found in COVID‐19‐infected patients with coexisting liver disease. As the virus can be identified in gastrointestinal contents, endoscopic procedures during the pandemic should be carefully selected and proper protection strategies should be encouraged to prevent viral transmission. |
| first_indexed | 2024-12-18T02:28:20Z |
| format | Article |
| id | doaj.art-77f39431007b46bdb74b3365208791f0 |
| institution | Directory Open Access Journal |
| issn | 2397-9070 |
| language | English |
| last_indexed | 2024-12-18T02:28:20Z |
| publishDate | 2021-11-01 |
| publisher | Wiley |
| record_format | Article |
| series | JGH Open |
| spelling | doaj.art-77f39431007b46bdb74b3365208791f02022-12-21T21:23:59ZengWileyJGH Open2397-90702021-11-015111257126510.1002/jgh3.12671Coronavirus disease 2019 gastrointestinal and liver manifestations in adults: A reviewApichet Sirinawasatien0Tanyaporn Chantarojanasiri1Sirina Ekpanyapong2Naris Tivatunsakul3Viravarn Luvira4Division of Gastroenterology, Department of Medicine, Rajavithi Hospital, College of Medicine Rungsit University Bangkok ThailandDivision of Gastroenterology, Department of Medicine, Rajavithi Hospital, College of Medicine Rungsit University Bangkok ThailandDivision of Gastroenterology, Department of Medicine, Rajavithi Hospital, College of Medicine Rungsit University Bangkok ThailandDivision of Gastroenterology, Department of Medicine Banpong Hospital Ratchaburi ThailandDepartment of Clinical Tropical Medicine, Faulty of Tropical Medicine Mahidol University Bangkok ThailandAbstract Coronavirus disease 2019 (COVID‐19) is an important health problem that has a serious adverse impact on the global economy and healthcare systems. The virus is not only involved in the respiratory system, but also causes other systemic effects as well as several gastrointestinal and liver issues. Evidence has shown direct viral invasion into the gastrointestinal tissue and supporting vascular network, causing various manifestations such as diarrhea, nausea, gastrointestinal bleeding, and abnormal liver function tests. The degree of gastrointestinal injury, especially in terms of liver involvement, is correlated with disease severity. There is no specific treatment for gastrointestinal involvement, and the symptoms can be managed with supportive therapy. Moreover, increased liver decompensation and mortality can be found in COVID‐19‐infected patients with coexisting liver disease. As the virus can be identified in gastrointestinal contents, endoscopic procedures during the pandemic should be carefully selected and proper protection strategies should be encouraged to prevent viral transmission.https://doi.org/10.1002/jgh3.12671angiotensin‐converting enzyme 2 receptorcoronavirus disease 2019diarrheagastrointestinalliversevere acute respiratory syndrome coronavirus 2 |
| spellingShingle | Apichet Sirinawasatien Tanyaporn Chantarojanasiri Sirina Ekpanyapong Naris Tivatunsakul Viravarn Luvira Coronavirus disease 2019 gastrointestinal and liver manifestations in adults: A review JGH Open angiotensin‐converting enzyme 2 receptor coronavirus disease 2019 diarrhea gastrointestinal liver severe acute respiratory syndrome coronavirus 2 |
| title | Coronavirus disease 2019 gastrointestinal and liver manifestations in adults: A review |
| title_full | Coronavirus disease 2019 gastrointestinal and liver manifestations in adults: A review |
| title_fullStr | Coronavirus disease 2019 gastrointestinal and liver manifestations in adults: A review |
| title_full_unstemmed | Coronavirus disease 2019 gastrointestinal and liver manifestations in adults: A review |
| title_short | Coronavirus disease 2019 gastrointestinal and liver manifestations in adults: A review |
| title_sort | coronavirus disease 2019 gastrointestinal and liver manifestations in adults a review |
| topic | angiotensin‐converting enzyme 2 receptor coronavirus disease 2019 diarrhea gastrointestinal liver severe acute respiratory syndrome coronavirus 2 |
| url | https://doi.org/10.1002/jgh3.12671 |
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