Novel biological markers for the diagnosis and prediction of mortality risk in patients with pulmonary embolism

Pulmonary embolism (PE) ranks third in the structure of death causes among all cardiovascular diseases after myocardial infarction and stroke. That is why the timely and earliest possible diagnosis of venous thromboembolism is of particular importance, which will help improve both short-term and lon...

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Main Authors: A. A. Podlipaeva, I. S. Mullova, T. V. Pavlova, E. V. Ushakova, D. V. Duplyakov
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2021-01-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/4202
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author A. A. Podlipaeva
I. S. Mullova
T. V. Pavlova
E. V. Ushakova
D. V. Duplyakov
author_facet A. A. Podlipaeva
I. S. Mullova
T. V. Pavlova
E. V. Ushakova
D. V. Duplyakov
author_sort A. A. Podlipaeva
collection DOAJ
description Pulmonary embolism (PE) ranks third in the structure of death causes among all cardiovascular diseases after myocardial infarction and stroke. That is why the timely and earliest possible diagnosis of venous thromboembolism is of particular importance, which will help improve both short-term and long-term patient prognosis. Given the low specificity of current laboratory parameters, such as D-dimer, NT-proBNP, cardiac troponin I, there is an urgent need to search for new biomarkers that can improve the quality of detection and stratification of VTE, including PE. A diagnostic and prognostic test for PE must be accurate, safe, easily accessible and inexpensive, as well as reproducible and non-invasive.This review presents the currently available literature data on the latest laboratory parameters that characterize right ventricular dysfunction due to PE and provide an evidence base for stratification of the death risk in this category of patients.
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spelling doaj.art-77f82ca3b1fb49c68e4633b984d013ee2023-03-29T21:23:37Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202021-01-01254S10.15829/1560-4071-2020-42023128Novel biological markers for the diagnosis and prediction of mortality risk in patients with pulmonary embolismA. A. Podlipaeva0I. S. Mullova1T. V. Pavlova2E. V. Ushakova3D. V. Duplyakov4Samara State Medical University; V.P. Polyakov Samara Regional Clinical Cardiology DispensarySamara State Medical University; V.P. Polyakov Samara Regional Clinical Cardiology DispensarySamara State Medical University; V.P. Polyakov Samara Regional Clinical Cardiology DispensaryV.P. Polyakov Samara Regional Clinical Cardiology DispensarySamara State Medical University; V.P. Polyakov Samara Regional Clinical Cardiology DispensaryPulmonary embolism (PE) ranks third in the structure of death causes among all cardiovascular diseases after myocardial infarction and stroke. That is why the timely and earliest possible diagnosis of venous thromboembolism is of particular importance, which will help improve both short-term and long-term patient prognosis. Given the low specificity of current laboratory parameters, such as D-dimer, NT-proBNP, cardiac troponin I, there is an urgent need to search for new biomarkers that can improve the quality of detection and stratification of VTE, including PE. A diagnostic and prognostic test for PE must be accurate, safe, easily accessible and inexpensive, as well as reproducible and non-invasive.This review presents the currently available literature data on the latest laboratory parameters that characterize right ventricular dysfunction due to PE and provide an evidence base for stratification of the death risk in this category of patients.https://russjcardiol.elpub.ru/jour/article/view/4202pulmonary embolismdeep vein thrombosismarkersoutcomesprognosis
spellingShingle A. A. Podlipaeva
I. S. Mullova
T. V. Pavlova
E. V. Ushakova
D. V. Duplyakov
Novel biological markers for the diagnosis and prediction of mortality risk in patients with pulmonary embolism
Российский кардиологический журнал
pulmonary embolism
deep vein thrombosis
markers
outcomes
prognosis
title Novel biological markers for the diagnosis and prediction of mortality risk in patients with pulmonary embolism
title_full Novel biological markers for the diagnosis and prediction of mortality risk in patients with pulmonary embolism
title_fullStr Novel biological markers for the diagnosis and prediction of mortality risk in patients with pulmonary embolism
title_full_unstemmed Novel biological markers for the diagnosis and prediction of mortality risk in patients with pulmonary embolism
title_short Novel biological markers for the diagnosis and prediction of mortality risk in patients with pulmonary embolism
title_sort novel biological markers for the diagnosis and prediction of mortality risk in patients with pulmonary embolism
topic pulmonary embolism
deep vein thrombosis
markers
outcomes
prognosis
url https://russjcardiol.elpub.ru/jour/article/view/4202
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AT evushakova novelbiologicalmarkersforthediagnosisandpredictionofmortalityriskinpatientswithpulmonaryembolism
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