Effect of cerebral microbleeds on hemorrhagic transformation and functional prognosis after intravenous thrombolysis of cerebral infarction
Hemorrhagic transformation is a common complication of acute cerebral infarction, and rtPA thrombolytic therapy will increase the risk of hemorrhagic transformation. Cerebral microbleeds (CMBs) have become an important and independent predictor of cerebral hemorrhage. However, it is still controvers...
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| Format: | Article |
| Language: | English |
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KeAi Communications Co., Ltd.
2022-09-01
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| Series: | Brain Hemorrhages |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589238X21000218 |
| _version_ | 1811309252738809856 |
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| author | Jinli Chen Kamil Duris Xiaobo Yang |
| author_facet | Jinli Chen Kamil Duris Xiaobo Yang |
| author_sort | Jinli Chen |
| collection | DOAJ |
| description | Hemorrhagic transformation is a common complication of acute cerebral infarction, and rtPA thrombolytic therapy will increase the risk of hemorrhagic transformation. Cerebral microbleeds (CMBs) have become an important and independent predictor of cerebral hemorrhage. However, it is still controversial whether CMBs increase the risk of intracranial hemorrhage (ICH) and poor prognosis (PFO) after intravenous thrombolysis (IVT) in patients with acute ischemic stroke (AIS).This review summarizes a number of studies on microbleeds in clinical patients, and discusses whether the presence, number, and distribution of CMBs are related to ICH and PFO after IVT in AIS patients, as well as the significance of CMBs in IVT decision-making in AIS. |
| first_indexed | 2024-04-13T09:38:58Z |
| format | Article |
| id | doaj.art-77f891d270aa455d8ce115fcfe0acf95 |
| institution | Directory Open Access Journal |
| issn | 2589-238X |
| language | English |
| last_indexed | 2024-04-13T09:38:58Z |
| publishDate | 2022-09-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Brain Hemorrhages |
| spelling | doaj.art-77f891d270aa455d8ce115fcfe0acf952022-12-22T02:52:00ZengKeAi Communications Co., Ltd.Brain Hemorrhages2589-238X2022-09-0133117119Effect of cerebral microbleeds on hemorrhagic transformation and functional prognosis after intravenous thrombolysis of cerebral infarctionJinli Chen0Kamil Duris1Xiaobo Yang2Department of Neurology, Pudong New District People's Hospital, Shanghai, PR ChinaDepartment of Pathological Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic; Department of Neurosurgery, The University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czech RepublicDepartment of Neurology, Jinshan Hospital, Fudan University, Shanghai, PR China; Corresponding author at: Department of Neurology, Jinshan Hospital, Fudan University, Shanghai, PR ChinaHemorrhagic transformation is a common complication of acute cerebral infarction, and rtPA thrombolytic therapy will increase the risk of hemorrhagic transformation. Cerebral microbleeds (CMBs) have become an important and independent predictor of cerebral hemorrhage. However, it is still controversial whether CMBs increase the risk of intracranial hemorrhage (ICH) and poor prognosis (PFO) after intravenous thrombolysis (IVT) in patients with acute ischemic stroke (AIS).This review summarizes a number of studies on microbleeds in clinical patients, and discusses whether the presence, number, and distribution of CMBs are related to ICH and PFO after IVT in AIS patients, as well as the significance of CMBs in IVT decision-making in AIS.http://www.sciencedirect.com/science/article/pii/S2589238X21000218Cerebral microbleedsIntravenous thrombolysisHemorrhagic transformation |
| spellingShingle | Jinli Chen Kamil Duris Xiaobo Yang Effect of cerebral microbleeds on hemorrhagic transformation and functional prognosis after intravenous thrombolysis of cerebral infarction Brain Hemorrhages Cerebral microbleeds Intravenous thrombolysis Hemorrhagic transformation |
| title | Effect of cerebral microbleeds on hemorrhagic transformation and functional prognosis after intravenous thrombolysis of cerebral infarction |
| title_full | Effect of cerebral microbleeds on hemorrhagic transformation and functional prognosis after intravenous thrombolysis of cerebral infarction |
| title_fullStr | Effect of cerebral microbleeds on hemorrhagic transformation and functional prognosis after intravenous thrombolysis of cerebral infarction |
| title_full_unstemmed | Effect of cerebral microbleeds on hemorrhagic transformation and functional prognosis after intravenous thrombolysis of cerebral infarction |
| title_short | Effect of cerebral microbleeds on hemorrhagic transformation and functional prognosis after intravenous thrombolysis of cerebral infarction |
| title_sort | effect of cerebral microbleeds on hemorrhagic transformation and functional prognosis after intravenous thrombolysis of cerebral infarction |
| topic | Cerebral microbleeds Intravenous thrombolysis Hemorrhagic transformation |
| url | http://www.sciencedirect.com/science/article/pii/S2589238X21000218 |
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