Crystal structure of the C-terminal domain of DENR
The density regulated protein (DENR) forms a stable heterodimer with malignant T-cell-amplified sequence 1 (MCT-1). DENR-MCT-1 heterodimer then participates in regulation of non-canonical translation initiation and ribosomal recycling. The N-terminal domain of DENR interacts with MCT-1 and carries a...
Main Authors: | Ivan B. Lomakin, Swastik De, Jimin Wang, Aditi N. Borkar, Thomas A. Steitz |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2020-01-01
|
Series: | Computational and Structural Biotechnology Journal |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2001037020300477 |
Similar Items
-
Crystal Structure of the Human Ribosome in Complex with DENR-MCT-1
by: Ivan B. Lomakin, et al.
Published: (2017-07-01) -
Abstract P-17: Structural and Functional Insights into Eukaryotic Translation Reinitiation and Ribosome Recycling Orchestrated by eIF2D and MCT-1/DENR
by: Desislava S. Makeeva, et al.
Published: (2019-06-01) -
Relocalization of Translation Termination and Ribosome Recycling Factors to Stress Granules Coincides with Elevated Stop-Codon Readthrough and Reinitiation Rates upon Oxidative Stress
by: Desislava S. Makeeva, et al.
Published: (2023-01-01) -
Model of the pathway of –1 frameshifting: Kinetics
by: Ping Xie
Published: (2016-03-01) -
Translation dysregulation in neurodegenerative diseases: a focus on ALS
by: Shaopeng Wang, et al.
Published: (2023-08-01)