Effects of sirtuin 1 deficiency on trophoblasts and its implications in the pathogenesis of pre-eclampsia

AbstractBackground Sirtuin 1 (SIRT1) is mainly localised in syncytiotrophoblasts and cytotrophoblasts, and is involved in pregnancy regulation. However, data on the association between SIRT1 and pre-eclampsia (PE) remains limited. This study aimed to investigate the role of SIRT1 in PE pathophysiolo...

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Bibliographic Details
Main Authors: Hongbiao Yu, Ling Chen, Ping Du, Xianping Liu, Ying Xia
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Journal of Obstetrics and Gynaecology
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/01443615.2023.2282103