Clinical characteristics of congenital heart defects in mild congenital anorectal malformation: single-centre experience
Abstract Objective To analyze the clinical characteristics and types of congenital heart defect (CHD) in mild congenital anorectal malformation (CARM), namely the rectoperineal and rectovestibular fistulas. Methods The retrospective study of 183 patients with mild CARM was conducted with assessments...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2024-01-01
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| Series: | BMC Pediatrics |
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| Online Access: | https://doi.org/10.1186/s12887-023-04518-9 |
| _version_ | 1797349720200314880 |
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| author | Wei Feng Minjie Zhang Jinping Hou Xiaohong Die Yi Wang Rong Liu |
| author_facet | Wei Feng Minjie Zhang Jinping Hou Xiaohong Die Yi Wang Rong Liu |
| author_sort | Wei Feng |
| collection | DOAJ |
| description | Abstract Objective To analyze the clinical characteristics and types of congenital heart defect (CHD) in mild congenital anorectal malformation (CARM), namely the rectoperineal and rectovestibular fistulas. Methods The retrospective study of 183 patients with mild CARM was conducted with assessments of demographic information, color Doppler echocardiography results, and follow-up data. We performed an analysis of the clinical characteristics of CHD, grouping them based on sex and type of mild CARM. Results Of the 183 patients, rectoperineal fistula occurred in 133 patients (72.7%), while the frequency of CHD was 79.8% (146/183). Ventricular septal defects (VSDs) occur more frequently in patients with rectoperineal fistula compared to those with rectovestibular fistula (1.5% vs. 10%), while the opposite trend was observed for patent ductus arteriosus (PDAs) (39.8% vs. 22.0%). Additionally, males presented higher frequency of PDA (42.7% vs. 26.4%) and self-healing (6 months: 87.2% vs. 42.6%; 12 months: 91.0% vs. 63.2%) than females. However, males had a lower rate of undergoing cardiac surgery (6.4% vs. 17.6%) and a younger median diagnosis age (1 day vs. 9 days). Conclusion Our study indicates that there is a necessity for meticulous cardiac assessment and follow-up in neonates diagnosed with mild CARM. |
| first_indexed | 2024-03-08T12:34:27Z |
| format | Article |
| id | doaj.art-7807ae90576b4e2d82aa5f11188335e1 |
| institution | Directory Open Access Journal |
| issn | 1471-2431 |
| language | English |
| last_indexed | 2024-03-08T12:34:27Z |
| publishDate | 2024-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pediatrics |
| spelling | doaj.art-7807ae90576b4e2d82aa5f11188335e12024-01-21T12:35:47ZengBMCBMC Pediatrics1471-24312024-01-0124111010.1186/s12887-023-04518-9Clinical characteristics of congenital heart defects in mild congenital anorectal malformation: single-centre experienceWei Feng0Minjie Zhang1Jinping Hou2Xiaohong Die3Yi Wang4Rong Liu5Department of General & Neonatal Surgery, Children’s Hospital of Chongqing Medical University; National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Structural Birth Defect and ReconstructionDepartment of General & Neonatal Surgery, Children’s Hospital of Chongqing Medical University; National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Structural Birth Defect and ReconstructionDepartment of General & Neonatal Surgery, Children’s Hospital of Chongqing Medical University; National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Structural Birth Defect and ReconstructionDepartment of General & Neonatal Surgery, Children’s Hospital of Chongqing Medical University; National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Structural Birth Defect and ReconstructionDepartment of General & Neonatal Surgery, Children’s Hospital of Chongqing Medical University; National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Structural Birth Defect and ReconstructionDepartment of General & Neonatal Surgery, Children’s Hospital of Chongqing Medical University; National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Structural Birth Defect and ReconstructionAbstract Objective To analyze the clinical characteristics and types of congenital heart defect (CHD) in mild congenital anorectal malformation (CARM), namely the rectoperineal and rectovestibular fistulas. Methods The retrospective study of 183 patients with mild CARM was conducted with assessments of demographic information, color Doppler echocardiography results, and follow-up data. We performed an analysis of the clinical characteristics of CHD, grouping them based on sex and type of mild CARM. Results Of the 183 patients, rectoperineal fistula occurred in 133 patients (72.7%), while the frequency of CHD was 79.8% (146/183). Ventricular septal defects (VSDs) occur more frequently in patients with rectoperineal fistula compared to those with rectovestibular fistula (1.5% vs. 10%), while the opposite trend was observed for patent ductus arteriosus (PDAs) (39.8% vs. 22.0%). Additionally, males presented higher frequency of PDA (42.7% vs. 26.4%) and self-healing (6 months: 87.2% vs. 42.6%; 12 months: 91.0% vs. 63.2%) than females. However, males had a lower rate of undergoing cardiac surgery (6.4% vs. 17.6%) and a younger median diagnosis age (1 day vs. 9 days). Conclusion Our study indicates that there is a necessity for meticulous cardiac assessment and follow-up in neonates diagnosed with mild CARM.https://doi.org/10.1186/s12887-023-04518-9Congenital heart defectCongenital anorectal malformationClinical characteristicSex difference |
| spellingShingle | Wei Feng Minjie Zhang Jinping Hou Xiaohong Die Yi Wang Rong Liu Clinical characteristics of congenital heart defects in mild congenital anorectal malformation: single-centre experience BMC Pediatrics Congenital heart defect Congenital anorectal malformation Clinical characteristic Sex difference |
| title | Clinical characteristics of congenital heart defects in mild congenital anorectal malformation: single-centre experience |
| title_full | Clinical characteristics of congenital heart defects in mild congenital anorectal malformation: single-centre experience |
| title_fullStr | Clinical characteristics of congenital heart defects in mild congenital anorectal malformation: single-centre experience |
| title_full_unstemmed | Clinical characteristics of congenital heart defects in mild congenital anorectal malformation: single-centre experience |
| title_short | Clinical characteristics of congenital heart defects in mild congenital anorectal malformation: single-centre experience |
| title_sort | clinical characteristics of congenital heart defects in mild congenital anorectal malformation single centre experience |
| topic | Congenital heart defect Congenital anorectal malformation Clinical characteristic Sex difference |
| url | https://doi.org/10.1186/s12887-023-04518-9 |
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