B7H3-dependent myeloid-derived suppressor cell recruitment and activation in pulmonary fibrosis

B7H3-dependent myeloid-derived suppressor cell recruitment and activation in pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease without effective curative therapy. Recent evidence shows increased circulating myeloid-derived suppressor cells (MDSCs) in cancer, inflammation, and fibrosis, with some of these cells expressing B7H3. We sought to investigat...

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Bibliographic Details
Main Authors: Tianju Liu, Francina Gonzalez De Los Santos, Andrew E. Rinke, Chuling Fang, Kevin R. Flaherty, Sem H. Phan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
B7H3
TERT
lung
fibrosis
myeloid-derived suppressor cell (MDSC)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.901349/full

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