Gelatin Matrix as Functional Biomaterial for Immobilization of Nanoparticles of Metal-Containing Compounds

The data concerning the synthesis and physicochemical characteristics of specific functional biomaterials—biopolymer-immobilized matrix systems based on gelatin as an array and chemical compounds, which include atoms of various metal elements—are systematized and discussed. The features of this biop...

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Main Author: Oleg V. Mikhailov
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Journal of Functional Biomaterials
Subjects:
Online Access:https://www.mdpi.com/2079-4983/14/2/92
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author Oleg V. Mikhailov
author_facet Oleg V. Mikhailov
author_sort Oleg V. Mikhailov
collection DOAJ
description The data concerning the synthesis and physicochemical characteristics of specific functional biomaterials—biopolymer-immobilized matrix systems based on gelatin as an array and chemical compounds, which include atoms of various metal elements—are systematized and discussed. The features of this biopolymer which determine the specific properties of the immobilized matrix systems formed by it and their reactivity, are noted. Data on gelatin-immobilized systems in which immobilized substances are elemental metals and coordination compounds formed as a result of redox processes, nucleophilic/electrophilic substitution reactions, and self-assembly (template synthesis), are presented. The possibilities of the practical use of metal-containing gelatin-immobilized systems are promising for the future; in particular, their potential in medicine and pharmacology as a vehicle for “targeted” drug delivery to various internal organs/tissues of the body, and, also, as potential biosensors is noted.
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spelling doaj.art-7807fa355f37491b888d64a4831a2f7b2023-11-16T21:24:33ZengMDPI AGJournal of Functional Biomaterials2079-49832023-02-011429210.3390/jfb14020092Gelatin Matrix as Functional Biomaterial for Immobilization of Nanoparticles of Metal-Containing CompoundsOleg V. Mikhailov0Department of Analytical Chemistry, Certification and Quality Management, Kazan National Research Technological University, 420015 Kazan, RussiaThe data concerning the synthesis and physicochemical characteristics of specific functional biomaterials—biopolymer-immobilized matrix systems based on gelatin as an array and chemical compounds, which include atoms of various metal elements—are systematized and discussed. The features of this biopolymer which determine the specific properties of the immobilized matrix systems formed by it and their reactivity, are noted. Data on gelatin-immobilized systems in which immobilized substances are elemental metals and coordination compounds formed as a result of redox processes, nucleophilic/electrophilic substitution reactions, and self-assembly (template synthesis), are presented. The possibilities of the practical use of metal-containing gelatin-immobilized systems are promising for the future; in particular, their potential in medicine and pharmacology as a vehicle for “targeted” drug delivery to various internal organs/tissues of the body, and, also, as potential biosensors is noted.https://www.mdpi.com/2079-4983/14/2/92functional biomaterialgelatinmetal-containing compoundmetal compleximmobilizationnanoparticles
spellingShingle Oleg V. Mikhailov
Gelatin Matrix as Functional Biomaterial for Immobilization of Nanoparticles of Metal-Containing Compounds
Journal of Functional Biomaterials
functional biomaterial
gelatin
metal-containing compound
metal complex
immobilization
nanoparticles
title Gelatin Matrix as Functional Biomaterial for Immobilization of Nanoparticles of Metal-Containing Compounds
title_full Gelatin Matrix as Functional Biomaterial for Immobilization of Nanoparticles of Metal-Containing Compounds
title_fullStr Gelatin Matrix as Functional Biomaterial for Immobilization of Nanoparticles of Metal-Containing Compounds
title_full_unstemmed Gelatin Matrix as Functional Biomaterial for Immobilization of Nanoparticles of Metal-Containing Compounds
title_short Gelatin Matrix as Functional Biomaterial for Immobilization of Nanoparticles of Metal-Containing Compounds
title_sort gelatin matrix as functional biomaterial for immobilization of nanoparticles of metal containing compounds
topic functional biomaterial
gelatin
metal-containing compound
metal complex
immobilization
nanoparticles
url https://www.mdpi.com/2079-4983/14/2/92
work_keys_str_mv AT olegvmikhailov gelatinmatrixasfunctionalbiomaterialforimmobilizationofnanoparticlesofmetalcontainingcompounds