Orbitofrontal and striatal metabolism, volume, thickness and structural connectivity in relation to social anhedonia in depression: A multimodal study

Orbitofrontal and striatal metabolism, volume, thickness and structural connectivity in relation to social anhedonia in depression: A multimodal study

Background: Social anhedonia is common within major depressive disorder (MDD) and associated with worse treatment outcomes. The orbitofrontal cortex (OFC) is implicated in both reward (medial OFC) and punishment (lateral OFC) in social decision making. Therefore, to understand the biology of social...

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Bibliographic Details
Main Authors: Brianna M. Donnelly, David T. Hsu, John Gardus, Junying Wang, Jie Yang, Ramin V. Parsey, Christine DeLorenzo
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:NeuroImage: Clinical
Subjects:
Major depression disorder
Social anhedonia
Brain imaging
Orbitofrontal cortex
SSRI treatment
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158223002449

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