Coiled-coil structure of meiosis protein TEX12 and conformational regulation by its C-terminal tip
The X-ray crystal structures of C-terminal mutants of the coiled-coil protein cancer testis antigen TEX12 in combination with modeling of the TEX12 wild-type dimer reveal the protein’s control of its oligomeric state, which resembles assembly of its complex with synaptonemal complex central element...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-09-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-022-03886-9 |