Frequency of Metabolic Syndrome in Patients with Chronic Obstructive Pulmonary Disease
Background and purpose: There are controversies on the relationship between metabolic syndrome and chronic obstructive pulmonary disease (COPD). The present study was done to determine the frequency of metabolic syndrome in male patients with COPD as well as the associated illnesses and the symptoms...
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| Format: | Article |
| Language: | English |
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Mazandaran University of Medical Sciences
2020-02-01
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| Series: | Journal of Mazandaran University of Medical Sciences |
| Subjects: | |
| Online Access: | http://jmums.mazums.ac.ir/article-1-12850-en.html |
| _version_ | 1797944079349186560 |
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| author | Mohammad Ali Zohal Afsaneh Sedighi Ali Akbar Shafikhani Seyed Amir Farzam |
| author_facet | Mohammad Ali Zohal Afsaneh Sedighi Ali Akbar Shafikhani Seyed Amir Farzam |
| author_sort | Mohammad Ali Zohal |
| collection | DOAJ |
| description | Background and purpose: There are controversies on the relationship between metabolic syndrome and chronic obstructive pulmonary disease (COPD). The present study was done to determine the frequency of metabolic syndrome in male patients with COPD as well as the associated illnesses and the symptoms of the disease.
Materials and methods: In a cross-sectional survey in Qazvin University of Medical Sciences, 2014, a total of 80 COPD men (33-87-year-old) were enrolled. For all patients, demographic characteristics were recorded, a spirometric examination was done, and metabolic syndrome indicators, systemic inflammation (CRP) levels, and CHARLSON index were measured. We used regression analysis, independent t-test, and ANOVA to analyze the data.
Results: The rate of metabolic syndrome was 37.5% in COPD patients. Patients with metabolic syndrome had more severe COPD, higher use of inhaled steroids, and fewer Forced expiratory volume in the first second (FEV1) than those who did not have metabolic syndrome (P<0.05). Diabetes (P= 0.009) and cardiac disorders (P= 0.023) showed a significant association with metabolic syndrome. Among the components of the metabolic syndrome, waist circumference, hypertension, and CRP had a significant association with airway obstruction (P<0.05).
Conclusion: The prevalence of metabolic syndrome was high in COPD patients. We also found an association between the airflow obstruction in more severe COPD stages and metabolic syndrome, hypertension, and waist circumference. |
| first_indexed | 2024-04-10T20:32:55Z |
| format | Article |
| id | doaj.art-78159cab99f048dbb1e8f8a22cd53162 |
| institution | Directory Open Access Journal |
| issn | 1735-9260 1735-9279 |
| language | English |
| last_indexed | 2024-04-10T20:32:55Z |
| publishDate | 2020-02-01 |
| publisher | Mazandaran University of Medical Sciences |
| record_format | Article |
| series | Journal of Mazandaran University of Medical Sciences |
| spelling | doaj.art-78159cab99f048dbb1e8f8a22cd531622023-01-25T05:06:32ZengMazandaran University of Medical SciencesJournal of Mazandaran University of Medical Sciences1735-92601735-92792020-02-0129182111116Frequency of Metabolic Syndrome in Patients with Chronic Obstructive Pulmonary DiseaseMohammad Ali Zohal0Afsaneh Sedighi1Ali Akbar Shafikhani2Seyed Amir Farzam3 Associate Professor, Department of Internal Medicine, Metabolic Disease Research Center, Qazvin University of Medical Sciences, Qazvin, Iran General Practitioner, Metabolic Disease Research Center, Qazvin University of Medical Sciences, Qazvin, Iran PhD Student in Occupational Health Engineering, Shahid Beheshti University of Medical Sciences, Tehran, Iran Assistant Professor, Department of Pathology, Metabolic Disease Research Center, Qazvin University of Medical Sciences, Qazvin, Iran Background and purpose: There are controversies on the relationship between metabolic syndrome and chronic obstructive pulmonary disease (COPD). The present study was done to determine the frequency of metabolic syndrome in male patients with COPD as well as the associated illnesses and the symptoms of the disease. Materials and methods: In a cross-sectional survey in Qazvin University of Medical Sciences, 2014, a total of 80 COPD men (33-87-year-old) were enrolled. For all patients, demographic characteristics were recorded, a spirometric examination was done, and metabolic syndrome indicators, systemic inflammation (CRP) levels, and CHARLSON index were measured. We used regression analysis, independent t-test, and ANOVA to analyze the data. Results: The rate of metabolic syndrome was 37.5% in COPD patients. Patients with metabolic syndrome had more severe COPD, higher use of inhaled steroids, and fewer Forced expiratory volume in the first second (FEV1) than those who did not have metabolic syndrome (P<0.05). Diabetes (P= 0.009) and cardiac disorders (P= 0.023) showed a significant association with metabolic syndrome. Among the components of the metabolic syndrome, waist circumference, hypertension, and CRP had a significant association with airway obstruction (P<0.05). Conclusion: The prevalence of metabolic syndrome was high in COPD patients. We also found an association between the airflow obstruction in more severe COPD stages and metabolic syndrome, hypertension, and waist circumference.http://jmums.mazums.ac.ir/article-1-12850-en.htmlmetabolic syndromechronic obstructive pulmonary diseasehypertensionwaist circumference |
| spellingShingle | Mohammad Ali Zohal Afsaneh Sedighi Ali Akbar Shafikhani Seyed Amir Farzam Frequency of Metabolic Syndrome in Patients with Chronic Obstructive Pulmonary Disease Journal of Mazandaran University of Medical Sciences metabolic syndrome chronic obstructive pulmonary disease hypertension waist circumference |
| title | Frequency of Metabolic Syndrome in Patients with Chronic Obstructive Pulmonary Disease |
| title_full | Frequency of Metabolic Syndrome in Patients with Chronic Obstructive Pulmonary Disease |
| title_fullStr | Frequency of Metabolic Syndrome in Patients with Chronic Obstructive Pulmonary Disease |
| title_full_unstemmed | Frequency of Metabolic Syndrome in Patients with Chronic Obstructive Pulmonary Disease |
| title_short | Frequency of Metabolic Syndrome in Patients with Chronic Obstructive Pulmonary Disease |
| title_sort | frequency of metabolic syndrome in patients with chronic obstructive pulmonary disease |
| topic | metabolic syndrome chronic obstructive pulmonary disease hypertension waist circumference |
| url | http://jmums.mazums.ac.ir/article-1-12850-en.html |
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