The impact of high-intensity interval training on vascular function in adults: A systematic review and meta-analysis
AimWe performed a systematic review and meta-analysis to investigate the effects of high-intensity interval training (HIIT) compared with moderate-intensity continuous training (MICT) or with no exercise (CON) on vascular function in adults who were free of cardiometabolic diseases and those with ca...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-11-01
|
| Series: | Frontiers in Cardiovascular Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2022.1046560/full |
| _version_ | 1811312184895995904 |
|---|---|
| author | Mousa Khalafi Mohammad Hossein Sakhaei Fatemeh Kazeminasab Michael E. Symonds Sara K. Rosenkranz |
| author_facet | Mousa Khalafi Mohammad Hossein Sakhaei Fatemeh Kazeminasab Michael E. Symonds Sara K. Rosenkranz |
| author_sort | Mousa Khalafi |
| collection | DOAJ |
| description | AimWe performed a systematic review and meta-analysis to investigate the effects of high-intensity interval training (HIIT) compared with moderate-intensity continuous training (MICT) or with no exercise (CON) on vascular function in adults who were free of cardiometabolic diseases and those with cardiometabolic diseases.MethodsA search across three electronic databases including Scopus, PubMed, and Web of Science was conducted through February 2022 to identify the randomized trials evaluating HIIT vs. MICT and/or CON on vascular function as measured using brachial artery flow-mediated dilation (FMD) in adults. Separate analyses were conducted for HIIT vs. MICT and/or CON to calculate weighted mean differences (WMD) and 95% confidence intervals (95% CIs) using random or fixed models.ResultsA total of 36 studies involving 1,437 participants who were either free of cardiometabolic diseases or had cardiometabolic diseases were included in the meta-analysis. HIIT effectively increased FMD when compared with MICT [1.59% (95% CI 0.87–2.31), p = 0.001] or CON [3.80% (95% CI 2.58–5.01), p = 0.001]. Subgroup analysis showed that HIIT increased FMD in participants with cardiovascular and metabolic diseases, but not in participants who were free of cardiometabolic diseases. In addition, HIIT effectively increased FMD regardless of age and body mass index.ConclusionWe confirm that HIIT is effective for improving vascular function in individuals with metabolic disorders and cardiovascular diseases and has a superior effect compared to MICT, demonstrating time efficiency.Systematic review registration[https://www.crd.york.ac.uk/prospero], identifier [CRD42022320863]. |
| first_indexed | 2024-04-13T10:31:41Z |
| format | Article |
| id | doaj.art-78178980dfb944bbb6c9c9a85f702ace |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-04-13T10:31:41Z |
| publishDate | 2022-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-78178980dfb944bbb6c9c9a85f702ace2022-12-22T02:50:09ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2022-11-01910.3389/fcvm.2022.10465601046560The impact of high-intensity interval training on vascular function in adults: A systematic review and meta-analysisMousa Khalafi0Mohammad Hossein Sakhaei1Fatemeh Kazeminasab2Michael E. Symonds3Sara K. Rosenkranz4Department of Physical Education and Sport Sciences, Faculty of Humanities, University of Kashan, Kashan, IranDepartment of Exercise Physiology, Faculty of Sport Sciences, University of Guilan, Guilan, IranDepartment of Physical Education and Sport Sciences, Faculty of Humanities, University of Kashan, Kashan, IranAcademic Unit of Population and Lifespan Sciences, Centre for Perinatal Research, School of Medicine, University of Nottingham, Nottingham, United KingdomDepartment of Kinesiology and Nutrition Sciences, University of Nevada, Las Vegas, Las Vegas, NV, United StatesAimWe performed a systematic review and meta-analysis to investigate the effects of high-intensity interval training (HIIT) compared with moderate-intensity continuous training (MICT) or with no exercise (CON) on vascular function in adults who were free of cardiometabolic diseases and those with cardiometabolic diseases.MethodsA search across three electronic databases including Scopus, PubMed, and Web of Science was conducted through February 2022 to identify the randomized trials evaluating HIIT vs. MICT and/or CON on vascular function as measured using brachial artery flow-mediated dilation (FMD) in adults. Separate analyses were conducted for HIIT vs. MICT and/or CON to calculate weighted mean differences (WMD) and 95% confidence intervals (95% CIs) using random or fixed models.ResultsA total of 36 studies involving 1,437 participants who were either free of cardiometabolic diseases or had cardiometabolic diseases were included in the meta-analysis. HIIT effectively increased FMD when compared with MICT [1.59% (95% CI 0.87–2.31), p = 0.001] or CON [3.80% (95% CI 2.58–5.01), p = 0.001]. Subgroup analysis showed that HIIT increased FMD in participants with cardiovascular and metabolic diseases, but not in participants who were free of cardiometabolic diseases. In addition, HIIT effectively increased FMD regardless of age and body mass index.ConclusionWe confirm that HIIT is effective for improving vascular function in individuals with metabolic disorders and cardiovascular diseases and has a superior effect compared to MICT, demonstrating time efficiency.Systematic review registration[https://www.crd.york.ac.uk/prospero], identifier [CRD42022320863].https://www.frontiersin.org/articles/10.3389/fcvm.2022.1046560/fullhigh-intensity interval trainingmoderate-intensity continuous trainingvascular functioncardiovascular diseasesmetabolic disorders |
| spellingShingle | Mousa Khalafi Mohammad Hossein Sakhaei Fatemeh Kazeminasab Michael E. Symonds Sara K. Rosenkranz The impact of high-intensity interval training on vascular function in adults: A systematic review and meta-analysis Frontiers in Cardiovascular Medicine high-intensity interval training moderate-intensity continuous training vascular function cardiovascular diseases metabolic disorders |
| title | The impact of high-intensity interval training on vascular function in adults: A systematic review and meta-analysis |
| title_full | The impact of high-intensity interval training on vascular function in adults: A systematic review and meta-analysis |
| title_fullStr | The impact of high-intensity interval training on vascular function in adults: A systematic review and meta-analysis |
| title_full_unstemmed | The impact of high-intensity interval training on vascular function in adults: A systematic review and meta-analysis |
| title_short | The impact of high-intensity interval training on vascular function in adults: A systematic review and meta-analysis |
| title_sort | impact of high intensity interval training on vascular function in adults a systematic review and meta analysis |
| topic | high-intensity interval training moderate-intensity continuous training vascular function cardiovascular diseases metabolic disorders |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2022.1046560/full |
| work_keys_str_mv | AT mousakhalafi theimpactofhighintensityintervaltrainingonvascularfunctioninadultsasystematicreviewandmetaanalysis AT mohammadhosseinsakhaei theimpactofhighintensityintervaltrainingonvascularfunctioninadultsasystematicreviewandmetaanalysis AT fatemehkazeminasab theimpactofhighintensityintervaltrainingonvascularfunctioninadultsasystematicreviewandmetaanalysis AT michaelesymonds theimpactofhighintensityintervaltrainingonvascularfunctioninadultsasystematicreviewandmetaanalysis AT sarakrosenkranz theimpactofhighintensityintervaltrainingonvascularfunctioninadultsasystematicreviewandmetaanalysis AT mousakhalafi impactofhighintensityintervaltrainingonvascularfunctioninadultsasystematicreviewandmetaanalysis AT mohammadhosseinsakhaei impactofhighintensityintervaltrainingonvascularfunctioninadultsasystematicreviewandmetaanalysis AT fatemehkazeminasab impactofhighintensityintervaltrainingonvascularfunctioninadultsasystematicreviewandmetaanalysis AT michaelesymonds impactofhighintensityintervaltrainingonvascularfunctioninadultsasystematicreviewandmetaanalysis AT sarakrosenkranz impactofhighintensityintervaltrainingonvascularfunctioninadultsasystematicreviewandmetaanalysis |